New biologically active ionic liquids with benzethonium cation‐efficient SAR inducers and antimicrobial agents

Abstract

BACKGROUNDAn urgent need to find new methods for crop protection remains open due to the withdrawal from the market of the most toxic pesticides and increasing consumer awareness. One of the alternatives that can be used in modern agriculture is the use of bifunctional compounds whose actions towards plant protection are wider than those of conventional pesticides.RESULTSIn this study, we present the investigation of the biological efficacy of 9 dual‐functional salts containing a SAR‐inducing anion and the benzethonium cation. A significant result of the presented study is the discovery of the SAR induction activity of benzethonium chloride, which was previously reported only as an antimicrobial agent. Moreover, the concept of dual functionality was proven, as the application of presented compounds in a given concentrations resulted both in the control of human and plant bacteria species and induction of SAR.CONCLUSIONThe strategy presented in this article shows the capabilities of derivatization of common biologically active compounds into their ionic derivatives to obtain bifunctional salts This approach may be an example of the design of potential new compounds for modern agriculture. It provide plants with two complementary actions allowing to provide efficient protection to plants, if one mode of action is ineffective.This article is protected by copyright. All rights reserved.

The Use of a New Ionic Derivative of Salicylic Acid in Sugar Beet Cultivation

“…Therefore, 3,5-dichlorosalicylic acid was the derivative and changed into an anionic form (3,5-dichlorosalicylate anion) and coupled with the choline cation responsible for increasing solubility of the compound and reducing phytotoxicity [22]. This approach was already successfully applied by our team for the derivatization of benzothiadiazoles and other structural analogues of salicylic acid [11,23,24].…”