New cobalt(II) Schiff base complex: Synthesis, characterization, DFT calculation and antimicrobial activity

Bis-ferrocenyl-hydrazide metal complexes: studying electronic functional groups as newly potent homogeneous photocatalysts for C(sp3)–H and C(sp2)–H bond oxidation utilizing visible light condition

“…55 A similar pattern was found for [(FcHz–OH) 2 Cu] (1598 and 1617 cm −1 ). 56 The [(FcHz–NO 2 ) 2 Ni] complex displayed two distinct and intense bands at 1600 and 1530 cm −1 , which are attributed to the amidate-CO and CN azomethine groups, respectively. The FT-IR spectrum of the [(FcHz–NO 2 ) 2 Cu] complex exhibited two significant signals at 1600 and 1530 cm −1 , which are indicative of the presence of the amidated-CO and CN azomethine moieties, 57 respectively.…”

Hydrolytically Stable TiIV–Hydrazone-Based Metallodrugs: Protein Interaction and Anticancer Potential

“…In current times, the design of many pharmaceutical medicines relies heavily on aroylhydrazones coupled with a heterocyclic moiety. , Isoniazid (isonicotinic acid hydrazide) is a popularly used antituberculosis commercial drug, whereas isoniazid-Schiff bases are found to exhibit preferable anticancer and antitubercular action over isoniazid. , Also, various heterocyclic hydrazones appended with pyridine and quinoline moieties exhibited improved pharmacological activities. , Additionally, it was found that the variable ring sizes and the heteroatoms of the heterocycles in hydrazones also have a significant impact on the selectivities, biomolecular interactions, hydrophobicity, and resulting toxicity profiles of cancer cells. ,, A recent study by our group revealed heterocyclic hydrazones containing dioxidovanadium­(V) complexes had favorable hydrophobic properties, biomolecular interactions, and significant anticancer activity . Another important finding of the study was that heterocyclic groups containing systems exhibit increased cytotoxicity with increasing ring size .…”

“…14,15 Isoniazid (isonicotinic acid hydrazide) is a popularly used antituberculosis commercial drug, 16 whereas isoniazid-Schiff bases are found to exhibit preferable anticancer and antitubercular action over isoniazid. 17,18 Also, various heterocyclic hydrazones appended with pyridine and quinoline moieties exhibited improved pharmacological activities. 19,20 Additionally, it was found that the variable ring sizes and the heteroatoms of the heterocycles in hydrazones also have a significant impact on the selectivities, biomolecular interactions, hydrophobicity, and resulting toxicity profiles of cancer cells.…”