New Daily Persistent Headache: Disease or Syndrome?

Prakash, Sanjay

doi:10.1111/head.12037

Cited by 3 publications

(7 citation statements)

References 6 publications

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“…There are reports which suggest that headache associated with the above mentioned signs can be a usual presentation of CCF, in up to 40-50% cases [10,11], but rare are those which point out headache as the only clinical symptom of CCF. These, CCF associated headaches, in small number of cases, can be presented as mimicking primary headaches [12], but in our patients it was a rare clinical phenotype of primary headache, NDPH. This type of headache is one of the most common and often difficult headache disorders for diagnosis and therapy.…”

Section: Discussionmentioning

confidence: 47%

“…On the other side, it must be borne in the mind that the absence of abnormalities on noninvasive imaging studies (as was in initial CT scanning in here presented case) does not exclude the diagnosis of CCF [13]. Thus, cerebral angiography presents the gold standard imaging modality in the diagnosis of CCF, which is useful in identifying the localization of fistula, evaluating venous drainage and assessing collateral circulation [12,13]. While low risk CCF with mild symptomatology can be managed conservatively, higher risk fistulas deserve the most aggressive approach in order to eradicate the fistula.…”

Section: Discussionmentioning

confidence: 75%

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New daily persistent headache — rare primary or secondary phenomena caused by carotid-cavernous fistula? A case report

et al. 2014

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AbstractCarotid cavernous fistulas (CCF) are dural arteriovenous fistulas which include pathological communications between the arterial system and the venous cavernous sinus situated at the wall of the cavernous sinus. It can be demonstrated by wide range clinical presentations. The presented case shows a very modest clinical presentation of CCF which was present over a few months only as new daily persistent headache without initial positive findings on performed computer tomography of the head, but rapidly worsened over a period of few days.

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Section: Discussionmentioning

confidence: 47%

Section: Discussionmentioning

confidence: 75%

New daily persistent headache — rare primary or secondary phenomena caused by carotid-cavernous fistula? A case report

et al. 2014

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“…The most typical presentation of NDPH is the acute onset headache on a specific day which becomes persistent within 24 hours. Most NDPH patients can recall the day when their headaches started (7,17,24). Hence, in the latest version of the ICHD, clearly remembering the onset is listed as a diagnostic criterion (9).…”

Section: Clinical Characteristicsmentioning

confidence: 99%

“…Headache features are not restricted, and migrainous features may be more common than TTH features (7,8,22,25,35), reflecting the evolution of the diagnostic criteria. Notably, despite the prominent migrainous features, most patients presented with bilateral headache that is commonly pressing/tightening (7,21,22,24). Previous headache disorders may exist in up to 29% of the patients with NDPH (7,8,17,22,24), but a chronification of preexisting headache disorders or de novo NDPH must be carefully differentiated based on the headache features changes, if any, and pre-NDPH headache frequency.…”

Section: Clinical Characteristicsmentioning

confidence: 99%

Update in the understanding of new daily persistent headache

Peng

Rozen

2023

Cephalalgia

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Background Accumulating evidence suggests various specific triggers may lead to new daily persistent headache (NDPH)-like presentations, suggesting that new daily persistent headache is a heterogenous syndrome, and challenging the concept that new daily persistent headache is a primary headache disorder. Method We searched the PubMed database up to August 2022 for keywords including persistent daily headache with both primary and secondary etiologies. We summarized the literature and provided a narrative review of the clinical presentation, diagnostic work-ups, possible pathophysiology, treatment response, and clinical outcomes. Results and conclusion New daily persistent headache is a controversial but clinically important topic. New daily persistent headache is likely not a single entity but a syndrome with different etiologies. The issue with past studies of new daily persistent headache is that patients with different etiologies/subtypes were pooled together. Different studies may investigate distinct subsets of patients, which renders the inter-study comparison, both positive and negative results, difficult. The identification (and removal) of a specific trigger might provide the opportunity for clinical improvement in certain patients, even when the disease has lasted for months or years. Nonetheless, if there is a specific trigger, it remains unknown or unidentified for a great proportion of the patients. We need to continue to study this unique headache population to better understand underlying pathogenesis and, most importantly, to establish effective treatment strategies that hopefully resolve the continuous cycle of pain.

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“…Perhaps NDPH is a heterogeneous disease entity, consisting of both primary and secondary etiologies. More specifically, as some have suggested, that NDPH is rather a syndrome than a distinct disease [ 11 ]. In the current review, we will focus on the progress of our understanding of NDPH over the last few years.…”

Section: Introductionmentioning

confidence: 99%

Update of New Daily Persistent Headache

Peng

Wang

2022

Curr Pain Headache Rep

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Purpose of Review The diagnostic criteria of new daily persistent headache (NDPH) have been revised since 2013. The current review focused on the progress of NDPH research over the last few years. Recent Findings Various new triggers and different NDPH mimics have been reported. The association with both cephalic and extracephalic pathologies suggests that NDPH is rather a syndrome with more than one disease mechanism. Recent clinical studies confirmed that migrainous headache remained the most prominent phenotype of NDPH, echoing the change of the diagnostic criteria in 2013. Diagnostic workup, including imaging studies, was unremarkable, except serving to exclude secondary etiologies. Studies on treatment options have yet shown promising targets, and randomized clinical trials are still lacking. Summary Multiple mechanisms, both cranial and systemic, may be involved synergically in the generation of NDPH-like headaches. The search for effective treatment options should base on better understanding of disease mechanisms.

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New Daily Persistent Headache: Disease or Syndrome?

Cited by 3 publications

References 6 publications

New daily persistent headache — rare primary or secondary phenomena caused by carotid-cavernous fistula? A case report

New daily persistent headache — rare primary or secondary phenomena caused by carotid-cavernous fistula? A case report

Update in the understanding of new daily persistent headache

Update of New Daily Persistent Headache

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