New dinuclear Schiff base complexes of iron(II/III) and copper(II) ions: synthesis, crystal structure, and DNA-binding studies

In vitro biological and in silico screening of novel iron(iii) complexes for DNA-targeted antitumor drug component

“…86 In addition, U-Wang et al demonstrated that the K b values of dinuclear Schiff base complexes of iron( ii / iii ) and copper( ii ) ions were found to be 7.1 × 10 4 M −1 and 7.9 × 10 4 M −1 , respectively. 87 It should be noted, that although we found significantly higher K b values for Fe1 and Fe2 than those reported by other researchers, they were lower than the K b values of the standard intercalator ethidium bromide ( K b = 7.0 × 10 7 M −1 ). 88,89 As a result, it was shown that Fe1 and Fe2 bind strongly to DNA by hypochromic and hyperchromic interactions.…”