New formulation calcium-based 45S5 bioactive glass: In vitro assessment in PBS solution for potential dental applications

Loh, Zhi Wei; Zaid, Mohd Hafiz Mohd; Kechik, Mohd Mustafa Awang; Fen, Yap Wing; Amin, Khamirul Matori; Cheong, Wei Mun

doi:10.1016/j.jmrt.2023.04.071

Cited by 10 publications

(1 citation statement)

References 62 publications

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“…Bioactive glass comes in various compositions, with prominent variant being 45S5 Bioglass, comprised of silicon dioxide (SiO 2 ): 45%, sodium oxide (Na 2 O): 24.5%, calcium oxide (CaO): 24.5%, and phosphorus pentoxide (P 2 O 5 ): 6% [ 24 ]. This variant, in particular, holds significant relevance within dentistry.…”

Section: Bioactive Glass Particles In Dentistrymentioning

confidence: 99%

A Review on Enhancing the Life of Teeth by Toothpaste Containing Bioactive Glass Particles

Prasad,

Pasha,

Rao

et al. 2024

Curr Oral Health Rep

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Purpose of Review Dental caries or tooth decay is one of the communal problems in the world which can affect not only the oral health but also the general health conditions. The main objective of this systematic review is to explore the efficacy of bioactive glass-based toothpastes against cariogenic bacteria. Recent Findings Bioactive glass particulates containing toothpaste show better remineralization potential on demineralized enamel and dentin when compared with toothpaste containing various bioactive constituents such as fluoride and potassium chloride. These constituents in conventional toothpaste can rapidly streak off due to acidic impact in the oral environment as the bioactive glass provides minerals for demineralized enamel and dentin by forming a strong hydroxyapatite (HAp) layer on its surface. Further, the therapeutic ions present in the bioglass can resist plaque formation by raising the pH of the surrounding environment or saliva and create amicable media for healthier teeth. Summary Toothpaste containing bioactive glass particles undoubtedly displayed the remineralizing potentiality of the dental hard tissues. Dynamics of the mineralization through different bioactive glass materials needs further investigations. In order to prevent dental cavities and improve oral health, it is important to identify and study different effective bioglass particles in toothpaste.

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Section: Bioactive Glass Particles In Dentistrymentioning

confidence: 99%