New Heterocycles Having Double Characters as Antimicrobial and Surface Active Agents. Part 1. Nonionic Compounds from Fatty Acid Isothiocyanate.

Amine, M. S.; Eissa, A. M. F.; El‐Sawy, A. A.; Shaaban, A. F.; El‐Sayed, Refat

doi:10.1002/chin.200550038

Cited by 17 publications

(25 citation statements)

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“…Treatment of Stearic acid with Thiosemicarbaziede in phosphorous oxy chloride produce 2-amino-5-heptadecyl-1,3,4-Thiadiazole-2-amine (1) [40].…”

Section: Resultsmentioning

confidence: 99%

Fatty Acids in Heterocyclic Synthesis. Part XVII: Synthesis of Non Ionic Surfactants Containing Piperidine, Piperazine, Imidazole Based on Thiadiazole and Microbiological Activities Evaluation

Abdelmajeid¹,

Amine²,

Hassan³

2017

IJOC

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A series of novel scaffolds Thiadiazolyl Piperidine, Thiadiazolyl Piperazine, thiadiazolidine, Thiadiazolyl thiazole and Thiadiazolyl-imidazole-Thione were synthesized from cheap, available and biologically active stearic acid. 2-amino-5-heptadecyl 1,3,4-thiadiazole reacts with chloroacetyl chloride and produced 2-choloro-N-(5-heptadecyl-1,3,4-Thiadiazole-2-yl) acetamide. Which allowed to react with Piperidine, Piperazine, urea and/or Thiourea and Potassium thiocyanate, and the latest scaffolds have been synthesized, respectively, and the structures of these compounds were established by elemental analysis, MS, IR and 1 H-NMR spectral data. The antimicrobial activities of the synthesized compounds were evaluated in-vitro against strains of gram +ve, gram −ve bacteria and fungi. Nonionic surfactant were obtained by addition of different moles of propylene oxide (3,5,7 mole) to the synthesized compounds bearing an active hydrogen. Physico-chemical and surface properties as well as biodegradability of the synthesized non-ionic surfactants were evaluated.

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“…Treatment of Stearic acid with Thiosemicarbaziede in phosphorous oxy chloride produce 2-amino-5-heptadecyl-1,3,4-Thiadiazole-2-amine (1) [40].…”

Section: Resultsmentioning

confidence: 99%

Fatty Acids in Heterocyclic Synthesis. Part XVII: Synthesis of Non Ionic Surfactants Containing Piperidine, Piperazine, Imidazole Based on Thiadiazole and Microbiological Activities Evaluation

Abdelmajeid¹,

Amine²,

Hassan³

2017

IJOC

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show abstract

“…Our approach to the synthesis of target molecules started from the condensation of 4-amino-acetophenone 1 with 4-hydroxy-3-methoxybenzaldehyde 2 by stirring in alkaline ethanolic solution to afford the chalcone derivative 3, which was stirred with stearoyl chloride 43 in dry acetone containing a catalytic amount of triethyl amine and given the adduct 4.…”

Section: Synthesismentioning

confidence: 99%

Potential Biosignificant Interest and Surface Activity of Efficient Heterocyclic Derivatives

El‐Sayed

Althagafi

2016

J. Oleo Sci.

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“…From the data, the emulsifying properties increase with decreasing number of ethylene oxide units and increase with increasing of alkyl chain (22) (c.f . Tables 3-6).…”

Section: Emulsifying Propertiesmentioning

confidence: 99%

Synthesis of Nonionic Surfactants by Treating Some Petroleum Derivatives

2012

Egypt. J. Chem.

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New Heterocycles Having Double Characters as Antimicrobial and Surface Active Agents. Part 1. Nonionic Compounds from Fatty Acid Isothiocyanate.

Abstract: For Abstract see ChemInform Abstract in Full Text.

Cited by 17 publications

References 0 publications

Fatty Acids in Heterocyclic Synthesis. Part XVII: Synthesis of Non Ionic Surfactants Containing Piperidine, Piperazine, Imidazole Based on Thiadiazole and Microbiological Activities Evaluation

Fatty Acids in Heterocyclic Synthesis. Part XVII: Synthesis of Non Ionic Surfactants Containing Piperidine, Piperazine, Imidazole Based on Thiadiazole and Microbiological Activities Evaluation

Potential Biosignificant Interest and Surface Activity of Efficient Heterocyclic Derivatives

Synthesis of Nonionic Surfactants by Treating Some Petroleum Derivatives

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