New Marker for Suspected Open Globe Injury (Perforation or Penetration): Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio

Abstract

Purpose: To compare the strength of the relationship between the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio(PLR) results of patients with or without open globe injury (perforation and penetration) in the acute period of orbital trauma.
 Materials and Methods: Forty patients with open globe injuryand twenty-five patients without open globe injury in the acute period of orbital trauma were enrolled in this retrospective study. Complete blood count measurement results of all subjects were assessed.
 Results: There was a significant difference in neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio between orbital trauma with open globe injury group and without open globe injury group (p=0.001, p=0.006).
 Conclusion: Our results of the blood count measurements suggest that the NLR and PLR at first three hours may predict ocular perforation/penetration and the clinicians have to alert are a risk factor of open globe injury.