New nanomaterials for the improvement of psoriatic lesions

Crışan, Maria; David, Luminiţa; Moldovan, Bianca; Vulcu, Adriana; Dreve, Simina; Perde-Schrepler, Maria; Tatomir, Corina; Filip, Gabriela Adriana; Bolfă, Pompei; Achim, Marcela; Chiorean, Ioana; Kacsó, Irina; Berghian‐Grosan, Camelia; Olenic, Liliana

doi:10.1039/c3tb20476f

Cited by 30 publications

(29 citation statements)

References 21 publications

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“…Each area was examined in greyscale mode in order to identify the morphological and structural parameters, with Doppler techniques and elastography. Part of our work concerning the role of ultrasound in the assessment of the therapeutic eicacy in plaque psoriasis patients was already published [16,17,21]. Therefore, in this study, we focused on the examination of the nail apparatus.…”

Section: Methodsmentioning

confidence: 99%

“…The local changes of the tissue elasticity corresponding to a psoriasis plaque are revealed in Related to the therapeutic approach in psoriasis patients, our group used high-frequency ultrasound to investigate the skin reaction after topical therapy with low potency steroids (cortisone) and natural extracts of cranberry and black elderberry, showing that ultrasound can evaluate with great accuracy the changes in psoriasis plaques induced by various topical therapies [16,17]. We assessed in a comparative manner the anti-inlammatory efect of the natural extracts of cranberry and black elderberry and of cortisone with control lesions only treated with emollients.…”

Section: An Interdisciplinary Approach To Psoriasismentioning

confidence: 99%

“…-Monitoring of various chronic inlammatory skin conditions and the eicacy of diferent local therapies [15][16][17].…”

Section: Sonography: General Considerationsmentioning

confidence: 99%

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Ultrasonography as a New, Non-Invasive Imagistic Technique Used for the Diagnosis and Monitoring of Psoriasis

Crışan¹,

Badea²,

Crişan³

et al. 2017

An Interdisciplinary Approach to Psoriasis

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Psoriasis is a chronic inlammatory autoimmune disease that involves the skin, nails, joints and other organs, being a systemic disease. Regardless of the clinical form, sonography can be efectively used to complete the clinical diagnosis. Aim:The identiication of non-invasive sonographic markers for the assessment of the severity of the disease and the eicacy of various therapies. Our study involved two research directions: (a) clinical and imagistic assessment of the skin and nail psoriasis lesions and (b) the imagistic evaluation of the therapeutic eicacy in psoriasis plaques and nail psoriasis by acquirement of sonographic images prior and after various therapies. Methods:In our prospective study, we used a multimodal evaluation of the disease, based on a non-invasive approach: clinical exam, dermoscopy, conventional and high frequency sonography, Doppler, power Doppler and elastography. Conclusions:Ultrasonography is an important tool for the non-invasive assessment of psoriatic lesions. It ofers speciic markers related to morphology, elasticity and blood supply of the lesions, improving the diagnosis and monitoring of the skin and nail lesions.

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Section: Methodsmentioning

confidence: 99%

Section: An Interdisciplinary Approach To Psoriasismentioning

confidence: 99%

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Ultrasonography as a New, Non-Invasive Imagistic Technique Used for the Diagnosis and Monitoring of Psoriasis

Crışan¹,

Badea²,

Crişan³

et al. 2017

An Interdisciplinary Approach to Psoriasis

Self Cite

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show abstract

“…Here, we present a part of our study and the use of an eco-friendly synthesis method which allowed us to obtain new nanomaterials based on gold / silver nanoparticles with anthocyanin molecules from fruit extracts of Viburnum opulus L. (VO), which contains the anthocyanin kuromanin chloride (K) as the ligand [63]. Comparatively, we have prepared, using the same method, nanomaterials with pure anthocyanin kuromanin chloride.…”

Section: Introductionmentioning

confidence: 99%

“…After the nanomaterials were analyzed from a toxicological point of view in vitro and in vivo [63][64][65][66][67][68], they were added to a cream base and used in medicine to treat psoriatic lesions. The results were statistically assessed.…”

Section: Introductionmentioning

confidence: 99%