New Schiff Base Crystal Ligand type [NO 2 ] derived from the interacting of 2-aminophenol with Glyoxylic acid, and its [N 2 O 4 ] Mn п Complex, Synthesizing and Characterizing

Sultan, Jasim Shihab; Alsalihi, Eman I.; Al-Fahdawi, Aeed S.; Jarad, Amer J.

doi:10.21608/ejchem.2019.17061.2052

Cited by 3 publications

(1 citation statement)

References 22 publications

(20 reference statements)

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“…As a result of the coordination between hexamethylenediamine and benzil, a new peak at (1500 cm -1 ) that belongs to the ʋ(C=N) [13] has appeared. and replaced by a new peak at (1500 cm -1 ) which is belongs to the ʋ(C=N) as a result of the coordination between hexamethylenediamine and benzyl [14]. In contrast to the spectra of the unbound ligand, which shows Schiff base reaction, a new peak at (1500 cm -1 ) belongs to the ʋ(C=N) as a result of coordination between hexamethylenediamine and benzil.…”

Section: Ligand's Ft-ir Spectrummentioning

confidence: 93%

Synthesis and characterization of benzil crown cyclic Schiff base ligand and its metal complexes

Alsalihi¹,

Al-khafaji²,

Al-fahdawi³

et al. 2022

Bull. Chem. Soc. Eth.

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ABSTRACT. The reaction between benzil and hexamethylenediamine formed a new ligand [L], [(1Z,3Z)-2,3-diphenyl-5,6,7,8,9,10-hexahydro-1,4-diazecine], of the type [N2], was synthesized by the condensation reaction through Schiff base reaction between benzil and hexamethylenediamine. The new Schiff base ligand reacts with Mnп, Niп and Coп metal ions to give the complexes with the general formula: [M(L)Cl2]. The elemental investigations have been used to analyze the ligand and its complexes by CHN, FT-IR, UV-Vis, TLC, mass spectrum, melting point with the study of biological activity to the formed compounds. From the data obtained, the proposed molecular structure adopts square planar structure about the metal ions. The study reveals the formation of a new ligand type [N2] and it's metal ion complexes with square planar structures metal:ligand ratio of 1:1, which can be employed in a variety of fields such as medicine and industry. KEY WORDS: Benzil, Hexamethylenediamine, Metal complexes, Square planar structure Bull. Chem. Soc. Ethiop. 2022, 36(4), 791-799. DOI: https://dx.doi.org/10.4314/bcse.v36i4.6

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Section: Ligand's Ft-ir Spectrummentioning

confidence: 93%

Synthesis and characterization of benzil crown cyclic Schiff base ligand and its metal complexes

Alsalihi¹,

Al-khafaji²,

Al-fahdawi³

et al. 2022

Bull. Chem. Soc. Eth.

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A Review on Synthesis and Biological Activities of 2‐Aminophenol‐Based Schiff Bases and Their Transition Metal Complexes

Rana,

Islam,

Islam

et al. 2024

Applied Organom Chemis

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ABSTRACT2‐Aminophenol‐based Schiff bases and their metal complexes have drawn a lot of interest because of their wide range of biological activity and their uses in several fields. These Schiff bases are synthesized through the condensation of 2‐aminophenol and various carbonyl compounds, and metal complexes formed easily by coordinating Schiff bases with transition metal ions possess a wide range of intriguing properties that have rendered them promising candidates in biomedical research. These compounds have a diverse array of captivating biological properties including antibacterial, antifungal, anticancer, and antioxidant actions. Their versatile nature and potential for tailored modifications hold the promise for innovative biomedical applications. Compared to standard antibiotics and other studied compounds, C2, C8–C11, and C116 complexes, along with L16 and L17 ligands, exhibit the highest antibacterial activity, while C3 and C115 complexes demonstrate the highest antifungal activity. The metal chelate formation of the ligands enhanced the antimicrobial activity by increasing their lipophilic nature. C66, C76, and C112 complexes and L39 ligand showed higher anticancer activity than standard anticancer drugs. The metal complexes have higher anticancer activity than the ligand due to improved permeability and cellular uptake. The anticancer activity of the complexes is related to the substituents of the Schiff base ligands. In compounds containing an electron‐withdrawing group (e.g., Cl or Br or NO2), the activity is obviously better than others. Ligands L1–L3 and L5, L6, and L32 demonstrated the most potent antioxidant activity, surpassing both metal complexes and standard conventional antioxidants. The ligands showed greater antioxidant activity than the metal complexes due to their capability of donating free protons to scavenge free radicals. More study is needed to fully explore the potential of 2‐aminophenol‐based Schiff bases and their transition metal complexes for the development of new drugs. This review summarizes different synthetic methods, biological activities, and the structure–activity relationship. This study aims to conduct further research on 2‐aminophenol‐based Schiff bases and their metal complexes.

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Synthesis, spectral studies, DFT, biological evaluation, molecular docking and dyeing performance of 1-(4-((2-amino-5-methoxy)diazenyl)phenyl) ethanone complexes with some metallic ions

Jarad

Dahi

Al‐Noor

et al. 2023

Journal of Molecular Structure

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New Schiff Base Crystal Ligand type [NO 2 ] derived from the interacting of 2-aminophenol with Glyoxylic acid, and its [N 2 O 4 ] Mn п Complex, Synthesizing and Characterizing

Cited by 3 publications

References 22 publications

Synthesis and characterization of benzil crown cyclic Schiff base ligand and its metal complexes

Synthesis and characterization of benzil crown cyclic Schiff base ligand and its metal complexes

A Review on Synthesis and Biological Activities of 2‐Aminophenol‐Based Schiff Bases and Their Transition Metal Complexes

Synthesis, spectral studies, DFT, biological evaluation, molecular docking and dyeing performance of 1-(4-((2-amino-5-methoxy)diazenyl)phenyl) ethanone complexes with some metallic ions

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