Newborn Infant Pain Assessment Using Heart Rate Variability Analysis

Abstract

The results of this study indicate that postoperative pain is associated with a decreased high-frequency HRV in full-term newborn infants. Our findings suggest that HRV could be used as an indicator to assess prolonged pain in the newborn infants.

Fetal Heart-Rate Variability: Validation of a New Continuous, Noninvasive Computerized Analysis

“…One study found that our method had a low sensitivity and specificity for postoperative acute-pain evaluation [26] ; yet, a majority of data indicate that our technology allows anesthetists to adapt analgesia during surgical procedures, labor, and postoperative recovery time [22-24, 26, 35] . We have also demonstrated that this method can be used to assess pain and discomfort in newborn and preterm infants [27] . This study is the first step in evaluating the ability of our method to assess fetal distress.…”

“…Many studies have demonstrated the ability of our index to investigate the autonomic response to painful stimuli in adults (both conscious and unconscious) [22][23][24][25][26] . We have also demonstrated that our method can be used to assess pain and discomfort in newborn and preterm infants [27] . Recent studies have highlighted that this method can also be used for the accurate prediction of the occurrence of hypoxemia [28] .…”

“…The FSI was then computed from the AUC min in order to obtain a value between 0 and 100: FSI = 100 * (a * AUC min + b)/12.8, where a = 5.1 and b = 1.2. The a and b values were determined empirically through the analysis of a dataset of more than 200 R-R records for both adult and pediatric patients in order to maintain good coherence between the visual aspect of the filtered R-R series and the quantitative measurement of the index [27,29,30] .…”

Validity and reliability of ALPS-Neo pain and stress assessment scale in newborns

“…Ağlama, kol ve bacak hareketleri, yüz kiriştirma, tonus değişiklikleri, inleme, huzursuzluk ve beslenme güçlüğü davranişsal tepkilerdendir [14,15]. Ağri sirasinda kalp atim hizinda artiş, solunumda değişiklikler ve oksijen satürasyonunda düşme fizyolojik belirtiler arasindadir [14,16]. Biyokimyasal tepki olarak; kortizol, katekolamin, büyüme hormonu, glukagon, renin ve aldesteron salgilanmasi artar, insülin salgilanmasi ise azalmaktadir [7,14,15,17,18].…”

Impact du cocooning et de la voix humaine sur le système nerveux autonome (SNA) de l’enfant grand prématuré

“…Nous avons évalué la VFC chez des nouveau-nés admis après un geste chirurgical. L'indice mesuré était significativement plus bas chez les enfants qui avaient un score d'EDIN élevé [14]. Dans une autre étude, nous avons évalué la VFC chez des nouveau-nés à la naissance après une extraction instrumentale : la VFC était significativement plus basse chez les enfants ayant un score d'EDIN élevé [15].…”