Newer Molecular Methods for the Surveillance of Antimalarial Resistanceby Using Non-Invasive Samples

Abstract

In Southeast Asian countries, Chloroquine and Primaquine combination therapy is most successful in treating uncomplicated Plasmodium vivax infections, for preventing relapses.Later, resistance to Chloroquine has emerged resulting in therapeutic failures, and this encouraged the research to identify causative factors (1). Several molecular methods have been developed to identify the genetic mechanisms involved in resistance to chloroquine and other