Newly Emerging Candida Specie: Should Clinicians and Mycologist be Concerned?

Abstract

The emergence of C. auris as a global nosocomial pathogen associated with multidrug resistance and high mortality rates has been recently discovered. This emerging pathogen appears to be far more able to induce systemic infection and mortality than other potential multi drug resistance (MDR) yeast pathogens even though it is found to have reduced virulence factors compared to C. albicans. There are issues with regard to the identification of C. auris using both phenotypic and molecular techniques; this has raised concerns about detecting the true scale of the problem. This mini- review elucidates on the literature available on C. auris and highlights the mechanism of pathogenesis and antifungal resistance, which will give further direction to extensive research in this field.