There is no doubt that new technology has become one of the crucial parts of most people’s lives around the world. By and large, in this era, the Internet and the Internet of Things (IoT) have become the most indispensable parts of our lives. Recently, IoT technologies have been regarded as the most broadly used tools among other technologies. The tools and the facilities of IoT technologies within the marketplace are part of Industry 4.0. The marketplace is too regarded as a new area that can be used with IoT technologies. One of the main purposes of this paper is to highlight using IoT technologies in Industry 4.0, and the Industrial Internet of Things (IIoT) is another feature revised. This paper focuses on the value of the IoT in the industrial domain in general; it reviews the IoT and focuses on its benefits and drawbacks, and presents some of the IoT applications, such as in transportation and healthcare. In addition, the trends and facts that are related to the IoT technologies on the marketplace are reviewed. Finally, the role of IoT in telemedicine and healthcare and the benefits of IoT technologies for COVID-19 are presented as well.