Nicotine pouches

Keogh, Aoife

doi:10.1038/s41415-021-2622-y

Cited by 11 publications

(7 citation statements)

References 3 publications

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“…Here we expand the existing ONP flavor wheel of snus (natural) and non-tobacco (synthetic) flavor wheel dividing them among the availability of their flavors and discrete brands marketing ONP in the US and Europe. ONPs has been marketed in U.S. and Europe as a substitute for tobacco smoking [1][2][3]. We could review that the European region demonstrates a large share of about 88% of Snus ONPs distributors whereas USA depicts about 12% of Snus distributors.…”

Section: Discussionmentioning

confidence: 99%

“…Oral Nicotine Pouches (ONPs) are a type of emerging smokeless tobacco product sold by some large tobacco companies [1]. Starting from Scandinavia, the selling of ONPs quickly spread to many other countries including the European Union, the UK, the US, and Japan [1][2][3]. The US Food and Drug Administration (FDA) closely describes these oral pouches as "ground, cut, leaf or powdered tobacco regularly available in moist or chew gum snuff often packed in a pre-portioned pouch [1,4].…”

Section: Introductionmentioning

confidence: 99%

“…[5,6]. The appearance of these tobacco-free pouches is similar to that of snus and similarly, the ONPs are placed in a user's anterior maxillary vestibule (between the gum and the lip) for chemicals to be released and absorbed [2,3]. Since 2016 the US [2,7] market consists of nicotine pouches that do not contain tobacco leaves in the final product, and since 2018 in Europe [2,8,9].…”

Section: Introductionmentioning

confidence: 99%

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Classification, Perception, Sociological Aspects, and Toxicity of Emerging Flavored Oral Nicotine Pouches

Shaikh¹,

Newton²,

Tung³

et al. 2023

Preprint

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Introduction: Oral Nicotine Pouches (ONPs) are the new form of nicotine pouches that have become a type of emerging smokeless tobacco product sold by various tobacco companies. These smokeless tobacco products are being marketed for usage all over as Snus containing tobacco-derived nicotine (Natural) or as tobacco-free nicotine (Synthetic) as substitutes for other tobacco products that are limited in public places. ONPs have become popular tobacco products among adolescents/young adults and over 50% of young adult users of ONP use flavored ONP, such as menthol/mint, tobacco, dessert/candy, and fruity, being the most popular flavors. Various new ONP flavors are currently popular locally as well in the online market. Tobacco, Menthol, and fruit-flavored ONPs could motivate cigarette smokers to alteration to ONPs. Methods: We expanded our knowledge on natural/synthetic ONP flavors wheels to available data on ONPs, describing in detail their flavors and brands (US and Europe) in both natural/Synthetic ONP categories. We classified over 152 snus and 228 synthetic ONPs into the following flavor categories: “Tobacco”, “Menthol/Mint”, “Fruity”, “Candy/Deserts”, “Drink”, “Aroma”, “Spices” and “Mixed Flavors”. Results: Based on total numbers, wefound that the most popular ONPs flavor sold as tobacco and menthol to be among natural ONPs, among synthetic ONPs fruity and menthol as the most prominent flavors with varying concentrations of nicotine and other flavoring chemicals including coolant WS-23. We also illustrated possible molecular targets and toxicities due to exposure to ONPs activating several signaling cascades like AKT and NF-B might possibly lead to apoptosis and epithelial mesenchymal transition (EMT). Conclusions: Considering the marketing of ONP products with various flavor profiles and most of these products containing tobacco/menthol/fruit flavor, it is likely to have regulation and marketing disclaimer on some of these products. Further, it would be logical to determine how the market reacts in terms of compliance and non-compliance with flavor restrictions by the regulatory agencies.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Classification, Perception, Sociological Aspects, and Toxicity of Emerging Flavored Oral Nicotine Pouches

Shaikh¹,

Newton²,

Tung³

et al. 2023

Preprint

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“…ONPs have emerged relatively more recently, primarily marketed online as non-combustible alternatives for tobacco and nicotine products 97 98. Data on perceptions are limited, though a recent survey in the Netherlands showed that users perceived nicotine pouches as less harmful, but not less addictive than other tobacco and nicotine products, including cigarettes 95.…”

Section: Addictiveness and Appeal Of Ends Htps And Onpsmentioning

confidence: 99%

Evolution of tobacco products: recent history and future directions

et al. 2022

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Declines in cigarette smoking prevalence in many countries and the consolidation of the tobacco industry have prompted the introduction of other forms of nicotine delivery. These include electronic nicotine delivery systems (ENDS), heated tobacco products (HTPs) and oral nicotine products (ONPs). Evolving over time, some of these products now deliver nicotine at levels comparable to cigarettes and may serve as effective substitutes for smokers. However, certain products, especially ENDS like JUUL, have also appealed to youth and non-smokers, prompting concerns about expanding nicotine use (and potentially nicotine addiction). The tobacco industry could shift away from primarily promoting cigarettes to promoting ENDS, HTPs and/or ONPs, though at this time it continues to heavily promote cigarettes in low and middle-income countries. Differing regulatory regimes may place upward and downward pressures on both cigarettes and these newer products in terms of population use, and may ultimately drive the extent to which cigarettes are or are not displaced by ENDS, HTPs and/or ONPs in the coming decade.

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“…NPs are small receptacles that contain white nicotine powder which a user places in between upper lip and gum, leaving nicotine to release. 1 These products are sold as preportioned pouches similar to snus, but instead of containing tobacco leaf, these are filled with white nicotine-containing powder extracted from tobacco leaves. 2 NPs are sold in a variety of fruit (e.g., black cherry, citrus) and other (e.g., peppermint, coffee) flavors, and vary in nicotine content per pouch (e.g., Dryft: 2 mg and 7 mg; Velo: 2 mg and 4 mg; Lyft: 4 mg and 6 mg).…”

Section: Introductionmentioning

confidence: 99%

Knowledge, attitudes, practices, and prevalence of nicotine pouches in Pakistan: where do we stand?

Nawaz,

Hameed,

Yasin

et al. 2023

Int J Community Med Public Health

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Background: Nicotine pouches (NPs) are a relatively new type of oral smokeless tobacco-free nicotine product which are considered an alternative nicotine delivery system to help quit smoking. There is little information available about the safety and composition of NPs, and yet they are being widely endorsed by various influential institutions. Our study aimed to assess knowledge, attitude, and practices (KAP) regarding NPs among the Pakistani population. Methods: A large cross-sectional study was conducted using an anonymous online survey. The survey included questions regarding demographics, and KAP of NPs. Descriptive, univariate and multivariate analyses were performed to establish any relationship between the exposure variables (sociodemographic factors) and the outcome variables (KAP scores). Results: A total of 1749 participants were included in the final analysis. The mean age of the respondents was 20.6 years. The overall mean score of knowledge and attitude was 3.0 and 4.75 respectively. Around 40.0% of participants had adequate knowledge while 50.6% had a negative attitude towards NPs. Overall, 17.2% of the respondents reported using NPs. Results showed that there was no difference in cigarettes used before and after the start of nicotine pouches (median=3, IQR=2-6). Conclusions: NPs are being marketed in Pakistan at a rapid rate despite very little information about their adverse effects. Our study demonstrates scanty knowledge of NP in the Pakistani population, and advocates education about harmful effects of NP. Larger interventional studies are needed to investigate potential adverse effects of NP consumption which can aid in the regulation and marketing of this product.

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Nicotine pouches

Cited by 11 publications

References 3 publications

Classification, Perception, Sociological Aspects, and Toxicity of Emerging Flavored Oral Nicotine Pouches

Classification, Perception, Sociological Aspects, and Toxicity of Emerging Flavored Oral Nicotine Pouches

Evolution of tobacco products: recent history and future directions

Knowledge, attitudes, practices, and prevalence of nicotine pouches in Pakistan: where do we stand?

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