Nigerian plants III. Phytochemical screening for alkaloids, saponins, and tannins

Persinos, Georgia J.; Quimby, Maynard W.

doi:10.1002/jps.2600561129

Cited by 32 publications

(14 citation statements)

References 3 publications

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“…Tannins have been identified in the leaves of all species except S. spinosa (Watt and Breyer-Brandwijk, 1962;Persinos and Quimby, 1967;Duquenois and Anton, 1968;Kerharo and Adam, 1974). However, our phytochemical screening did not allow us to identify them in our methylene chloride extracts, so the observed activity must be due to other classes of compounds.…”

Section: Discussionmentioning

confidence: 88%

In vitro antitrypanosomal activity of ethnopharmacologically selected Beninese plants

Hoet

Opperdoes

Brun

et al. 2004

Journal of Ethnopharmacology

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The in vitro antitrypanosomal activity of methylene chloride, methanol and aqueous extracts of the leaves and twigs of five plant species traditionally used in Benin for the treatment of sleeping sickness were evaluated on Trypanosoma brucei brucei and their selectivity was analysed on Leishmania mexicana mexicana and J774 macrophage-like murine cells. The results showed that the four most active extracts had MIC values ≤19 g/ml (Hymenocardia acida twig and leaf, Strychnos spinosa leaf, Trichilia emetica leaf methylene chloride extracts).All these extracts had a lower activity on L. m. mexicana and J774 cells. Determination of the IC 50 values of the methylene chloride leaf extracts on two strains of trypanosomes (T. b. brucei and T. b. rhodesiense) and two mammalian cell lines (L6 and J774 cells) showed that all extracts possessed some antitrypanosomal activity with IC 50 's ranging from 1.5 to 39 g/ml. All were also toxic to the mammalian cells, but usually with higher IC 50 's. The only exception was the S. spinosa methylene chloride leaf extract which had no toxicity on J774 cells. Although tannins have been identified in most of the species studied, they could not be detected in the most active extracts, just as alkaloids. The presence of flavonoids and quinones may at least in part explain the observed activities of some of the active extracts.

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Section: Discussionmentioning

confidence: 88%

In vitro antitrypanosomal activity of ethnopharmacologically selected Beninese plants

Hoet

Opperdoes

Brun

et al. 2004

Journal of Ethnopharmacology

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“…One ml extract without addition of the gelatine-salt reagent was used as control. The presence of tannins was confirmed by the black colour produced with ferric chloride solution (FeCl 3 , 2%) (Persinos and Quimby, 1967).…”

Section: Determination Of the Linkages Present In The Polysaccharidesmentioning

confidence: 99%

Medicinal use of Cochlospermum tinctorium in Mali

Nergård

Diallo

Inngjerdingen

et al. 2005

Journal of Ethnopharmacology

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“…To identify the phytoconstituents, ethanolic extract of T. tricuspidata roots were subjected to preliminary phytochemical screening (Kokate, 1994;Harborne et al, 2005;Persinos et al, 1967;Peach, 1955), which was carried out using standard procedure.…”

Section: Phytochemical Screeningmentioning

confidence: 99%

Anti-hyperglycemic activity of <i>Trichosanthes tricuspidata</i> root extract

Kulandaivel

Bajpai

Sivakumar

2013

Bangladesh J Pharmacol

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To evaluate the anti-diabetic activity of ethanolic extract of Trichosanthes tricuspidata root in alloxan induced diabetic rats and to perform the phytochemical screening. The extraction, preliminary phytochemical screening, anti -diabetic activity in alloxan induced diabetic rats by oral administration of extract (200 and 400 mg/kg b.w.), the blood glucose level and biochemical parameters like cholesterol, triglyceride, serum protein, SGPT, SGOT, and ALP were estimated. Phytochemical studies shows the presence of carbohydrates, proteins, glycosides and terpenoids and the ethanolic extract of T. tricuspidata root significantly lowered the blood sugar level. The above findings justified the traditional claim of anti-diabetic activity in this plant. Article Info

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Nigerian plants III. Phytochemical screening for alkaloids, saponins, and tannins

Cited by 32 publications

References 3 publications

In vitro antitrypanosomal activity of ethnopharmacologically selected Beninese plants

In vitro antitrypanosomal activity of ethnopharmacologically selected Beninese plants

Medicinal use of Cochlospermum tinctorium in Mali

Anti-hyperglycemic activity of <i>Trichosanthes tricuspidata</i> root extract

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