Night shiftwork and prostate-specific antigen level in a tire manufacturing factory

Abstract

BackgroundRecent studies suggest that night shiftwork may increase the risk of prostate cancer and elevated serum prostate-specific antigen (PSA) level. The purpose of this study was to verify whether rotating night shiftwork affects serum PSA level.MethodsThis study included 3,195 male production workers who work in a large tire manufacturing factory. Serum PSA levels were measured and the data on related factors were obtained.ResultsThe mean serum PSA level was 0.98 ± 0.79 ng/mL. PSA levels were significantly lower in the younger age group, the obese group, and regular exercise group. PSA levels were lower in night shift workers (n = 2,832) compared to day workers (n = 363), but the difference was not statistically significant.ConclusionsUnlike previous studies, we did not find any evidence that night shiftwork results in an increase in serum PSA levels. Further research and consistent results are needed to elucidate the association between night shiftwork and the effect on the prostate.

Consequences of Shift Work and Night Work: A Literature Review

“…In the metabolic system subcategory (n = 13), there was an emphasis on the problems of the system itself [94][95][96][97][98][99][100], obesity [60,104], and diabetes [85,[101][102][103]. The association between breast cancer [105][106][107][108][109][110] or prostate cancer [111,112] and work schedules was studied several times, representing a total of 10 references to oncological problems. Both the immune system [50,[115][116][117][118][119], as well as well-being and quality of life [69,71,[120][121][122][123], had six references each.…”

A Longitudinal Study of the Relationship between Shift Work and Prostate-Specific Antigen in Healthy Male Workers

“…A study of the National Health and Nutrition Examination Survey reported an association with shift work and elevated PSA levels, which implicates that shift workers had a higher risk of developing prostate cancer [ 21 ]. On the other hand, another study of Korean workers in tire manufacturing indicated that night shift work did not show increased PSA levels [ 22 ]. Although there have been many studies on the relationship between shift work and prostate cancer, there is still the need for further research because of the inconsistency of the relationship [ 12 , 23 , 24 , 25 ].…”