Nine new tropane alkaloids from Datura stramonium L. identified by GC/MS

Bazaoui, Ahmed El; Bellimam, My Ahmed; Soulaymani, Abdelmajid

doi:10.1016/j.fitote.2010.09.010

Cited by 76 publications

(42 citation statements)

References 21 publications

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“…Examples include Datura stramonium L., which is one of the most widely studied plant species from a phytochemical standpoint (Berkov et al 2005) and from which more than 60 different TAs have been isolated (Bazaoui et al 2011). In an attempt to mitigate any discrepancies brought about by calculation of the number of occurrences alone, we calculated the diversity index of ornithine-derived alkaloids (TAs and CAs) ( Table I).…”

Section: Resultsmentioning

confidence: 99%

Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae

Pigatto

Blanco

Mentz

et al. 2015

An. Acad. Bras. Ciênc.

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This study assessed the occurrence and distribution of tropane alkaloids and calystegines in genera of the family Solanaceae to identify patterns of distribution and make evolutionary inferences. A database of tropane alkaloids and calystegines occurrences was constructed from the results of a search of scientific websites and a hand search of periodicals. The terms "Solanaceae", "tropane alkaloids", and "calystegines" were used as index terms for a full-text article search unrestricted by date of publications. The number of occurrence and chemical diversity indices were calculated and cluster analysis and principal components analysis were performed. Overall, 996 occurrences were reported, 879 of tropane alkaloids (88.3%) and 117 of calystegines (11.7%). The calystegines were significantly more relevant than tropane alkaloids for characterization of distinct groups of genera on both analyses performed here. This corroborates the trend toward a chemical dichotomy observed on database analysis and somewhat reinforces the correlation between geographic distribution and occurrence of secondary metabolites, as the presence of calystegines alone (without tropane alkaloids) was only reported in genera that have South America as their center of diversity.

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Section: Resultsmentioning

confidence: 99%

Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae

Pigatto

Blanco

Mentz

et al. 2015

An. Acad. Bras. Ciênc.

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“…Datura innoxia is an attractive medicinal plant [1] which is a rich source of a variety of natural products and secondary metabolites. Among these tropane alkaloids, hyoscyamine and hyoscine are clinically more significant [2][3][4][5]. Different plant parts or their extracts have been used traditionally for the cure of common diseases and ailmentssuch as asthma, cough, convulsion, Parkinson disease, catarrhal inflammation, epilepsy, rheumatism, piles, dysmenorrhea, various skin problems and infected wounds [6].…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of hyoscine in wild-type and <i>in vitro</i> grown <i>Datura innoxia</i> by high performance liquid chromatography

Siddiqui¹,

Khurshid²,

Roomi³

et al. 2017

Trop. J. Pharm Res

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“…Eight alkaloid compounds were identified in ethanolic extract of D. stramonium [13]. Nine new tropane alkaloids were identified in D. Stramonium by GC-MS by El Bazaoui et al [14]. By considering the above mentioned facts, plant samples of Datura stramonium, D. metel, Argemone mexicana and commercial sample of 'Pan masala' (Pan masala is a mixture of betle leaf, lime, areca nut,tobaco and other spices.…”

Section: Introductionmentioning

confidence: 99%

Identification of Atropine and Scopolamine from Datura L. Plant and Market Samples by GC-MS

Dendukuri¹,

Ravikumar²,

Amaraneni³

2017

Asian J. Chem.

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Datura plant which generally grows as weed, is also used for medicinal purposes. The plant is narcotic and used to treat skin diseases and rheumatic pain. Atropine and scopolamine are the main alkaloids in the plant. Atropine is antimuscuranic whereas, scopolamine affects central nervous system. In the present study, the presence of atropine and scopolamine were verified in leaves and seeds of Datura stramonium and D. metel. Argemone mexicana which is another weed is also generally identified as 'Datturi' and a popular chewing product called 'pan masala' were also subjected to GC-MS analysis. Hexane extracts did not show the presence of atropine and scopolamine. However, ethyl acetate and methanol extracts of both species of Datura elucidated the presence of alkaloids. Argemone mexicana and 'Pan masala' did not show the presence of atropine and scopolamine. This confirms that Argemone mexicana, is not an alternate to Datura and commercial 'Pan masala' does not contains the alkaloids.

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Nine new tropane alkaloids from Datura stramonium L. identified by GC/MS

Cited by 76 publications

References 21 publications

Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae

Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae

Comparative analysis of hyoscine in wild-type and <i>in vitro</i> grown <i>Datura innoxia</i> by high performance liquid chromatography

Identification of Atropine and Scopolamine from Datura L. Plant and Market Samples by GC-MS

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