Nitric Oxide Is Associated with Long-Term Zinc Tolerance in <i>Solanum nigrum</i>

Xu, Jin; Yin, Houfa; Li, Yulong; Liu, Xiaojing

doi:10.1104/pp.110.162982

Cited by 165 publications

(112 citation statements)

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“…In this work, we showed that copper induced a biphasic increase in NO level that is dependent on NO synthase activity, calcium release, and electron transport in organelles. In this sense, it has been shown that copper and other heavy metals induced NO synthesis in plants and that its synthesis is dependent on an NO synthase-like activity (Tewari et al, 2008;Ramos et al, 2009;Singh et al, 2009;Xiong et al, 2010;Xu et al, 2010). In addition, it was determined that NO synthesis is dependent on calcium release in N. plumbaginifolia and grapevine (Lamotte et al, 2006;Vandelle et al, 2006).…”

Section: Calcium Activates Antioxidant Protein Gene Expression Via Camentioning

confidence: 99%

“…On the other hand, heavy metals and metalloids such as copper, zinc, cadmium, aluminum, and arsenic induced NO synthesis in plants that is dependent on an NO synthase-like activity (Tewari et al, 2008;Ramos et al, 2009;Singh et al, 2009;Xiong et al, 2010;Xu et al, 2010). In addition, it was demonstrated that NO synthase is activated by calcium via CaMs in Arabidopsis (Ma et al, 2008).…”

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confidence: 96%

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Cross Talk among Calcium, Hydrogen Peroxide, and Nitric Oxide and Activation of Gene Expression Involving Calmodulins and Calcium-Dependent Protein Kinases in Ulva compressa Exposed to Copper Excess

et al. 2012

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To analyze the copper-induced cross talk among calcium, nitric oxide (NO), and hydrogen peroxide (H2O2) and the calcium-dependent activation of gene expression, the marine alga Ulva compressa was treated with the inhibitors of calcium channels, ned-19, ryanodine, and xestospongin C, of chloroplasts and mitochondrial electron transport chains, 3-(3,4-dichlorophenyl)-1,1-dimethylurea and antimycin A, of pyruvate dehydrogenase, moniliformin, of calmodulins, N-(6-aminohexyl)-5-chloro-1-naphtalene sulfonamide, and of calcium-dependent protein kinases, staurosporine, as well as with the scavengers of NO, 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, and of H2O2, ascorbate, and exposed to a sublethal concentration of copper (10 μm) for 24 h. The level of NO increased at 2 and 12 h. The first peak was inhibited by ned-19 and 3-(2,3-dichlorophenyl)-1,1-dimethylurea and the second peak by ned-19 and antimycin A, indicating that NO synthesis is dependent on calcium release and occurs in organelles. The level of H2O2 increased at 2, 3, and 12 h and was inhibited by ned-19, ryanodine, xestospongin C, and moniliformin, indicating that H2O2 accumulation is dependent on calcium release and Krebs cycle activity. In addition, pyruvate dehydrogenase, 2-oxoxglutarate dehydrogenase, and isocitrate dehydrogenase activities of the Krebs cycle increased at 2, 3, 12, and/or 14 h, and these increases were inhibited in vitro by EGTA, a calcium chelating agent. Calcium release at 2, 3, and 12 h was inhibited by 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide and ascorbate, indicating activation by NO and H2O2. In addition, the level of antioxidant protein gene transcripts decreased with N-(6-aminohexyl)-5-chloro-1-naphtalene sulfonamide and staurosporine. Thus, there is a copper-induced cross talk among calcium, H2O2, and NO and a calcium-dependent activation of gene expression involving calmodulins and calcium-dependent protein kinases.

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Section: Calcium Activates Antioxidant Protein Gene Expression Via Camentioning

confidence: 99%

mentioning

confidence: 96%

Cross Talk among Calcium, Hydrogen Peroxide, and Nitric Oxide and Activation of Gene Expression Involving Calmodulins and Calcium-Dependent Protein Kinases in Ulva compressa Exposed to Copper Excess

et al. 2012

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“…[28][29][30] However, NO can have both protective and cytotoxic effects depending on its concentration and location in the plant cells. 30 Since NO is short-lived and cytotoxic at high concentrations, GSNO could be a proper candidate for bioavailability of NO under physiological and stress conditions.…”

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confidence: 99%

Interactive effects of nitric oxide and glutathione in mitigating copper toxicity of rice (Oryza sativaL.) seedlings

Mostofa

Seraj

Fujita

2015

Plant Signaling & Behavior

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Nitric oxide (NO) and glutathione (GSH) are 2 vital components of the antioxidant system that play diverse roles in plant responses to abiotic stresses. Recently, we have reported that exogenous supply of both these molecules reduced copper (Cu) toxicity in rice seedlings. Individual as well as co-treatment of sodium nitroprusside (SNP: a NO donor) and GSH with Cu significantly mitigated the adverse effects of Cu, evident in the reduced level of oxidative markers such as H 2 O 2 , superoxide (O 2 ¢¡ ), malondialdehyde (MDA), and proline (Pro). GSH content and most of the antioxidative and glyoxalase enzymes were up-regulated upon Cu stress, indicating their responses were co-related with the level of stress. Our results indicated that direct ROS scavenging, reduced Cu uptake, and the balanced antioxidative and glyoxalase systems, at least in part, successfully executed NO-and GSH-mediated alleviation of Cu toxicity in rice seedlings. In addition, the combined effect of adding SNP and GSH together was more efficient than the effect of adding them individually. Here, we are speculating that 1) GSH and Pro could be used as potential markers for copper stress, and 2) adding SNP and GSH might produce S-nitrosoglutathione (GSNO) which could be a source of bioactive NO and may affect many regulatory processes involved in Cu-stress tolerance. We further note that the combined effect of adding SNP and GSH was pronounced in inhibiting the uptake and translocation of Cu in rice seedlings.

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“…However, an increase in NO was detected in H. verticillata plants exposed to Zn on Day 4, suggesting that excess Zn induced the generation of NO. High Zninduced NO was also found in the terrestrial plants Brassica juncea, Pisum sativum, and Solanum nigrum (Bartha et al 2005, J. Xu et al 2010. Increased NO concentration may be produced by peroxisomes and mitochondria and by the activity of nitrate reductase in plant cells (Xiong et al 2010).…”

Section: Discussionmentioning

confidence: 99%

“…Antioxidant enzymes like superoxide dismutase (SOD), ascorbate peroxidase (APX), catalase (CAT) and guaiacol peroxidase (POD), as well as antioxidant concentrations (for example ascorbic acid) are activated by plants to alleviate oxidative stress (Wójcik et al 2006, Tewari et al 2008, Wang et al 2009). Zn stress can also induce the generation of nitric oxide (NO), an important stress-response hormone (Bartha et al 2005, J. Xu et al 2010. A recent report showed that NO was associated with longterm Zn tolerance in Solanum nigrum (J.…”

Section: Introductionmentioning

confidence: 99%

Effects of nitric oxide on zinc tolerance of the submerged macrophyte Hydrilla verticillata

Zhang¹,

Liu²,

Lv³

et al. 2014

Aquat. Biol.

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Heavy metal pollution has become an increasingly recognized threat to the aquatic environment. In response to heavy metal stresses, various terrestrial plants produce the hormone nitric oxide (NO), but minimal information is available about the role of NO in aquatic macrophytes under high zinc (Zn) stress. In this study, we measured physiochemical parameters in the leaves of Hydrilla verticillata exposed to Zn 2+ (10 mg l ) for 10 d. NO application partially reversed Zn-induced negative effects in parameters such as nutrient uptake, antioxidant enzymatic activities, and biomass, as compared to treatments with Zn alone. These results indicate that NO supply could mitigate Zn stress in H. verticillata, as a defense mechanism of the plant against Zn toxicity.

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Nitric Oxide Is Associated with Long-Term Zinc Tolerance in Solanum nigrum

Cited by 165 publications

References 58 publications

Cross Talk among Calcium, Hydrogen Peroxide, and Nitric Oxide and Activation of Gene Expression Involving Calmodulins and Calcium-Dependent Protein Kinases in Ulva compressa Exposed to Copper Excess

Cross Talk among Calcium, Hydrogen Peroxide, and Nitric Oxide and Activation of Gene Expression Involving Calmodulins and Calcium-Dependent Protein Kinases in Ulva compressa Exposed to Copper Excess

Interactive effects of nitric oxide and glutathione in mitigating copper toxicity of rice (Oryza sativaL.) seedlings

Effects of nitric oxide on zinc tolerance of the submerged macrophyte Hydrilla verticillata

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