NMR Analysis of the interaction of Ethanol With the Nicotinic Acetylcholine Receptor

Abstract

Abbreviations:C50, concentration which elicits 50% of effective response; EDTA, ethylenediaminetetraacetic acid; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; Kd, dissociation constant, concentration at which complex is 50% dissociated; nAChR, nicotinic acetylcholine receptor; NMR, nuclear magnetic resonance; NOESY, nuclear Overhauser effect spectroscopy; Pi, inorganic phosphate, PO4 2-; NLS, nonlinear least squares.peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission.The copyright holder for this preprint (which was not . http://dx.doi.org/10.1101/139717 doi: bioRxiv preprint first posted online May. 18, 2017;

Notes on Synthesis of Perdeutero-5-13C,5,5,5-Trifluoroisoleucine VI56

“…Trace quantities of 2-13 C-trifluoroacetate have been characterized by 13 C- 19 F NMR coupling. This contribution may pave the way to future study [57][58][59].…”

Notes On Synthesis Of Perdeutero-5-13C,5,5,5-Trifluoroisoleucine VI

“…This work is part of a project to invigorate heteronuclear multidimensional NMR. See references 56,57,58 .…”