Nodular goiter (epidemiology and diagnostics)

Chernikov, Roman; Vorobjov, Sigrid; Slepzov, I V; Семенов, А А; Чинчук, И. К.; Makaryin, V.; Kulyash, A G; Uspenskaya, Anna; Timofeyeva, N I; Novokshonov, K Yu; Karelin, Yu V; Федоров, Е А; Isheyskaya, M S; Fedotov, Y N; Бубнов, А Н

doi:10.14341/ket20139229-35

Cited by 5 publications

(2 citation statements)

References 5 publications

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“…Surgical treatment of thyroid gland (TG) diseases is one of the priority areas in modern medical science as the number of patients with thyroid pathology is constantly increasing. Therefore, the prevalence of thyroidopathies in the Russian Federation averages at 10%, and morbidity rate is 50 new cases per 100 000 population per year [1][2][3]. Consequently, the number of surgical interventions on the thyroid gland inevitably increases.…”

Section: Introductionmentioning

confidence: 99%

“…Consequently, the number of surgical interventions on the thyroid gland inevitably increases. Owing to the possibility of conducting adequate replacement therapy with synthetic analogues of levothyroxine, thyroidectomy has become the operation of choice in treatment of not only thyroid malignancies, but also most benign thyroid diseases [2,3]. However, this type of surgical intervention can lead to failure of the parathyroid glands (PTG) function, caused by their injury or impaired blood supply [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

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Postoperative Hypoparathyroidism: Prognosis, Prevention, and Treatment (Review)

Melikyan¹,

Меньков²

2020

Sovrem Tehnol Med

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This review summarizes the results of studies concerning the problem of post-surgical hypoparathyroidism, a common complication of thyroid gland surgery, decreasing the quality of life in patients and, in some cases, leading to disability. A search for publications was carried out in electronic databases Web of Science, Scopus, Academic Search Complete (EBSCO), eLIBRARY, using keywords. The search depth was 7-10 years. Prevalence of post-surgical hypoparathyroidism was evaluated, the pathogenetic causes of the disease development, its clinical forms, methods of diagnosis and treatment were studied. It has been found that there is no single algorithm for analyzing the prognostic factors for the development of this pathological condition. It is emphasized that drug therapy of post-surgical hypoparathyroidism has a number of adverse effects. Therefore, the issues of prevention and surgical correction are of particular relevance. However, controversial opinions of contemporary authors about their clinical effectiveness determine the scientific and practical significance of further research on these issues.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Postoperative Hypoparathyroidism: Prognosis, Prevention, and Treatment (Review)

Melikyan¹,

Меньков²

2020

Sovrem Tehnol Med

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Stratification of thyroid nodules by Eu-TIRADS categories using transfer learning of convolutional neural networks

et al. 2022

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The article describes a method for assessing the malignancy potential of thyroid nodules and their stratification according to the European Thyroid Imaging And Reporting Data System (Eu-TIRADS) scale based on ultrasound diagnostic images using an artificial intelligence system. The method is based on the use of transfer learning technology for multi-parameter models of convolutional neural networks and their subsequent fine tuning. It was shown that even on a small dataset consisting of 1129 thyroid ultrasound images classified by 5 Eu-TIRADS categories, the application of the method provides high training accuracy (Accuracy: 0.8, AUC: 0.92). This makes it possible to introduce and use this technology in clinical practice as an additional tool (‘second opinion’) for an objective assessment of the risk of malignancy in thyroid nodules for the purpose of their further selection for fine needle biopsy.

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Experience of using vacuum fine-needle aspiration biopsy under ultrasound control in patients with focal thyroid pathology

Борсуков

Tagil

2021

Endo Serg

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Background: Due to its availability, high information content and harmlessness, ultrasound is an extremely effective method of differential diagnosis of thyroid pathology. Despite the sufficient arsenal of diagnostic methods, thyroid biopsy with cytological examination is the «gold» standard in diagnostic algorithms. Most often, fine — needle aspiration biopsy is carried out using disposable syringes of different capacities (5, 10, 20 ml3). The procedure is performed in most cases according to the «Free hand» method, this leads to several problems associated with the peculiarity of the study, primarily with the low vacuum created in the syringe and insufficient collection of cytological material, as well as insufficient practical experience for a novice specialist.Aim: Determination of the range of the possibility of using vacuum aspiration fine needle biopsy under the control of ultrasound navigation in patients with focal thyroid pathology.Materials and methods: On the basis of the Problem Research Laboratory «Diagnostic studies and minimally invasive technologies» of the Smolensk State Medical University, a device for vacuum fine — needle aspiration biopsy was developed. In the period 2019–2020, 780 vacuum fine — needle aspiration biopsy was performed under the control of ultrasound navigation in patients with thyroid nodules. The level of vacuum in the syringe during sampling of the material was — 0,5 bar (- 50 kPa).Results: A comparative analysis of the cytological results obtained with the help of vacuum fine — needle aspiration biopsy and the «Free hand» method shows a decrease in obtaining the category of Bethesda 1 by 3.3% and Bethesda 3 by 10.2%.Conclusion: This indicates the effectiveness and in formativeness of the use of vacuum fine — needle aspiration biopsy in patients with focal thyroid pathology in comparison with the standard «Free hand» method, as well as with vacuum fine — needle aspiration biopsy due to constant visual monitoring and the lack of movement of the syringe piston to create a discharge when taking cytological material, the probability of needle deviation from the biopsy zone is reduced, which increases the effectiveness of the study and facilitates the work of a novice specialist.

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Nodular goiter (epidemiology and diagnostics)

Cited by 5 publications

References 5 publications

Postoperative Hypoparathyroidism: Prognosis, Prevention, and Treatment (Review)

Postoperative Hypoparathyroidism: Prognosis, Prevention, and Treatment (Review)

Stratification of thyroid nodules by Eu-TIRADS categories using transfer learning of convolutional neural networks

Experience of using vacuum fine-needle aspiration biopsy under ultrasound control in patients with focal thyroid pathology

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