Nodular localized primary cutaneous amyloidosis and primary marginal zone B‐cell lymphoma on the nose: treatment with microscopically controlled surgery

Immunohistochemical study of immunoglobulin light chains and inflammatory cells in a patient with localized primary cutaneous nodular amyloidosis

“…10 However, the immunohistochemical results of amyloid deposits for lambda and kappa light chains are variable. [2][3][4][5][6][7][8][9] Our observation demonstrated that the amorphous material was strongly positive for kappa chains and weakly positive for lambda chains, indicating that the amyloid deposits may stem from polyclonal plasma cells.…”

“…[1][2][3] Immunohistochemical studies demonstrate disparate results of the amyloid deposits and plasmocytes for immunoglobulin kappa and lambda light chains. [3][4][5][6][7][8][9] We report a case of localized PCNA on the nose treated by excision and flap reconstruction.…”

Clinical presentation, therapeutic approach and outcome of primary cutaneous marginal zone B‐cell lymphoma presenting as AL amyloidoma of the skin

“…Cutaneous AL amyloidoma refers to indolent localized deposits of amyloid derived from immunoglobulin light chains (AL protein) produced by plasma cells, without systemic AL amyloidosis . PCMZBCL presenting as skin amyloidoma has been rarely reported …”