Nomogram Predictive of Pathological Inguinal Lymph Node Involvement in Patients With Squamous Cell Carcinoma of the Penis

Ficarra, Vincenzo; Zattoni, Filiberto; Artibani, Walter; Fandella, A.; Martignoni, Guido; Novara, Giacomo; Galetti, T. Prayer; Zambolin, T.; Kattan, Michael W.

doi:10.1016/s0022-5347(05)01003-7

Cited by 149 publications

(77 citation statements)

References 13 publications

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“…Epidemiological analysis of the penile cancer cases corroborates the national and international literature on the theme, since most cases affect men ≥ 60 years [26][27][28]. About 60% of the cases occur in men ≥ 65 years, however, young individuals may also be affected, as about 22% of the cases are registered in patients ≤ 40 years and 7% in patients ≤ 30 years of age.…”

Section: Discussionsupporting

confidence: 64%

Profile of Patients with Penile Neoplasms Who Have Undergone Penectomy

Figueiroa

Menezes

Tavares³

et al. 2017

int arch med

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Introduction: Penile cancer accounts for 10% to 20% of the male urogenital tumors. In Brazil, the North and Northeast regions have the highest rates.Objective: Analytical, retrospective, and cross-sectional study addressing the profile of individuals with penile neoplasms who have undergone penectomy in Recife, Pernambuco, Brazil. Results: Poor hygiene, smoking, and phimosis were the main risk factors identified. Patients showed epidermoid carcinoma (type I) and metastasis. The early signs and symptoms were tumor and painful ulcer. Methods:

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Section: Discussionsupporting

confidence: 64%

Profile of Patients with Penile Neoplasms Who Have Undergone Penectomy

Figueiroa

Menezes

Tavares³

et al. 2017

int arch med

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“…This stratification has been adopted by the European Association of Urology in its guidelines on penile cancer. 1 45 have recently published a nomogram for predicting the likelihood of nodal metastasis using tumour thickness, growth pattern, grade, lymphovascular invasion, corpus cavernosum invasion, corpus spongiosum invasion, urethral infiltration and clinical node status. Prospective external validation will further delineate its ultimate utility.…”

Section: Risk Stratification In Penile Cancermentioning

confidence: 99%

What next? Managing lymph nodes in men with penile cancer

Leveridge

Morash

2013

CUAJ

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The management of patients with squamous cell carcinoma of the penis is often daunting given its rarity and subsequent lack of high-level evidence to support our decision-making. This culminates in the complex surgical issues involving the management of the regional lymph nodes, which is of critical importance to both quantity and quality of life for these patients. This review aims to highlight the decisive issues surrounding the management of the pelvic and inguinal lymph nodes in the setting of squamous cell carcinoma of the penis, and to spotlight recently published information that adds credence to accepted management strategies of both the clinically positive and negative groin after successful management of the primary lesion.

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“…In a subsequent study tumor stage, vascular invasion, and a proportion of greater than 50% poorly differentiated cancer were shown to be independent prognostic factors for lymph node metastasis (46). More recently a nomogram has been developed which incorporates stage, grade, tumor thickness, histologic growth pattern, vascular/lymphatic embolization, and clinical node status in order to calculate the probability of the inguinal area being pathologically positive (51).…”

Section: Assessment Of the Inguinal Nodesmentioning

confidence: 99%

Update in the management of penile cancer

et al. 2009

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Purpose: The management of penile cancer has evolved as less invasive techniques are applied in the treatment of the primary tumor and inguinal lymph nodes. Materials and Methods: Herein we review the literature focusing on advances in the preservation of the phallus as well as less morbid procedures to evaluate and treat the groins. Results: Promising imaging modalities for staging are discussed. New techniques are described and tables provided for penile preservation. We also review the contemporary morbidity of modified surgical forms for evaluation of the inguinal nodes. Conclusions: Advances in surgical technique have made phallic preservation possible in a greater number of primary penile cancers. The groins can be evaluated for metastasis with greater accuracy through new radiologic means as well as with less morbid modified surgical techniques.

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Nomogram Predictive of Pathological Inguinal Lymph Node Involvement in Patients With Squamous Cell Carcinoma of the Penis

Cited by 149 publications

References 13 publications

Profile of Patients with Penile Neoplasms Who Have Undergone Penectomy

Profile of Patients with Penile Neoplasms Who Have Undergone Penectomy

What next? Managing lymph nodes in men with penile cancer

Update in the management of penile cancer

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