Non-Invasive Drug Delivery Systems

Vllasaliu, Driton

doi:10.3390/pharmaceutics13050611

Cited by 7 publications

(1 citation statement)

References 15 publications

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“…Furthermore, concerns about needle disposal hinder parenteral administration [23]. There are significant advantages to non-invasive drug delivery over injection, including a decreased risk of needle sticks, a low risk of infection, and an increased level of patient compliance with treatment [24,25].…”

Section: Non-invasive Drug Deliverymentioning

confidence: 99%

A Review of Non-Invasive Drug Delivery through Respiratory Routes

Zhang

Bai

et al. 2022

Pharmaceutics

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With rapid and non-invasive characteristics, the respiratory route of administration has drawn significant attention compared with the limitations of conventional routes. Respiratory delivery can bypass the physiological barrier to achieve local and systemic disease treatment. A scientometric analysis and review were used to analyze how respiratory delivery can contribute to local and systemic therapy. The literature data obtained from the Web of Science Core Collection database showed an increasing worldwide tendency toward respiratory delivery from 1998 to 2020. Keywords analysis suggested that nasal and pulmonary drug delivery are the leading research topics in respiratory delivery. Based on the results of scientometric analysis, the research hotspots mainly included therapy for central nervous systems (CNS) disorders (Parkinson’s disease, Alzheimer’s disease, depression, glioblastoma, and epilepsy), tracheal and bronchial or lung diseases (chronic obstructive pulmonary disease, asthma, acute lung injury or respiratory distress syndrome, lung cancer, and idiopathic pulmonary fibrosis), and systemic diseases (diabetes and COVID-19). The study of advanced preparations contained nano drug delivery systems of the respiratory route, drug delivery barriers investigation (blood-brain barrier, BBB), and chitosan-based biomaterials for respiratory delivery. These results provided researchers with future research directions related to respiratory delivery.

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Section: Non-invasive Drug Deliverymentioning

confidence: 99%