Non-traumatic Ectopia Lentis in a Pediatric Ophthalmology Practice, Ibadan, Nigeria

Abstract

PURPOSE: The aim of this study is to describe the clinical profile of patients with non-traumatic Ectopia lentis in a pediatric ophthalmology clinic in Ibadan, Nigeria.METHODS: The clinical records of children ≤ 16 years diagnosed with non- traumatic ectopia lentis at the Pediatric Ophthalmology Clinic, University College Hospital Ibadan, from May 1, 2015 to Dec 31, 2019 were retrospectively reviewed. Information on demographic data, family history, visual acuity (VA), mean refractive error (spherical equivalent), and management was retrieved.RESULTS: Clinical records of 25 patients were reviewed. The mean age was 8.9 (±3.41) years with a range of 2-15 years. Sixteen (64%) patients were males. All the patients had bilateral involvement. A positive family history of ectopia lentis was elicited in 6 (24%) patients. Thirteen (52%) patients had a Marfanoid habitus and superior displacement of the lens was observed in 26(52%) eyes. The presenting visual acuity was ≤ 6/36 in 38 (76%) eyes. The spherical equivalent of the refractive errors ranged from -20.00DS to +13.25DS. Twenty (40%) eyes underwent surgery within the period of the study and the best corrected postoperative visual acuity improved by 2 or more lines in 12 (60%) of operated eyes.CONCLUSION: Severe visual morbidity was common in this cohort of patients with Ectopia lentis in our practice. Treatment provided some improvement in vision which highlights the need to encourage early presentation for care. Detailed family history is important as a few of the patients were diagnosed on our request to examine siblings with visual impairment.