Nonadherence in Outpatient Thrombosis Prophylaxis with Low Molecular Weight Heparins after Major Orthopaedic Surgery

Wilke, Thomas; Moock, Jörn; Müller, Sabrina; Pfannkuche, Matthias; Kurth, Andreas

doi:10.1007/s11999-010-1306-8

Cited by 43 publications

(49 citation statements)

References 45 publications

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“…Over Despite major efforts to ensure systematic implementation into clinical practice (32,36), our results also demonstrated that adherence to ACCP guidelines has decreased significantly over the last 10 years and the gap between the guidelines recommendations and their implementation in clinical practice is still present (5,(36)(37)(38)(39).…”

Section: Discussionmentioning

confidence: 64%

Worldwide adherence to ACCP guidelines for thromboprophylaxis after major orthopedic surgery: A systematic review of the literature and meta-analysis

Farfan

Bautista

Bonilla

et al. 2016

Thrombosis Research

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Section: Discussionmentioning

confidence: 64%

Worldwide adherence to ACCP guidelines for thromboprophylaxis after major orthopedic surgery: A systematic review of the literature and meta-analysis

Farfan

Bautista

Bonilla

et al. 2016

Thrombosis Research

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“…The available evidence shows that self-reporting underestimates the extent of NA [61][62][63][64]. In this regard, the inclusion of other indicators such as administrative data or Medication Event Monitoring System/pill counts would considerably increase the validity of the NA measurement [34,65,66]. Limited data availability, however, is the challenge here.…”

Section: Discussionmentioning

confidence: 99%

“…In the first survey, 1177 patients were interviewed by a structured telephone interview. This survey was originally conducted to assess the extent of NA in outpatient thromboprophylaxis after major orthopedic surgery [34]. The interviewed patients were drawn from 22 German acute or rehabilitation orthopedic clinics (informed consent).…”

Section: Methodsmentioning

confidence: 99%

“…Even though many questions remain unresolved, it is apparent that these factors are capable of explaining a considerable part of the NA [10]. In this regard, negative general attitudes and negative medication beliefs [33,34] as well as inadequate coping behavior [35][36][37][38] and a poor relationship with health-care providers [26,39,40] are the most important.…”

Section: Introductionmentioning

confidence: 99%

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Toward Identifying the Causes and Combinations of Causes Increasing the Risks of Nonadherence to Medical Regimens: Combined Results of Two German Self-Report Surveys

2011

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“…Education has also been considered an important aspect to enforce VTE prophylaxis [7]. This has been shown to improve patient outcomes and adherence [18,19].…”

Section: Transition Into the Outpatient Settingmentioning

confidence: 99%

Continuation of venous thromboembolism prophylaxis after hospital discharge into the outpatient setting: the ACCEPT study

Schellong

Kaiser

Bramlage

2014

J Thromb Thrombolysis

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Transition from the hospital into the outpatient setting is a critical event for the appropriate provision of VTE prophylaxis. Data for this transition for the situation in Germany is scant. This was a retrospective, observational study in patients receiving in-hospital thromboprophylaxis and discharged with or without a recommendation to continue. Patient with previous thromboembolism were excluded. A total of 3,211 patients were identified by 518 physicians of which 2,853 had all data available for the present analysis; mean patient's age was 57.4 ± 17.5 (SD) years, 48.2% were male and bodyweight was 79.8 ± 16.1 kg. During hospitalization 95.5% of surgical and 84.0% of medical patients received any thromboprophylaxis, the mean hospital duration being 12.7 ± 20.3 days. Surgical patients had high, medium and low risk in 53.8, 37.1 and 9.1%, respectively. Medical patients had high, medium and low risk in 78.8, 19.8 and 1.4%. A hospital recommendation to continue thromboprophylaxis was given to 84.6% (95% CI 83.1-85.9%) of surgical and 64.9% (95% CI 59.1-70.6%) of medical patients and implemented in 96.6 and 94.3%, respectively. On the other hand, in patients without a respective hospital recommendation (15.4% of surgical and 35.1% of medical patients), thromboprophylaxis was continued in 65.3% of surgical and 73.1% of medical patients because of high risk. Our data illustrate acceptable rates of prophylaxis in surgical and medical patients in Germany. As the results show, it is essential that not only hospital physicians are aware of the actual risk at discharge, but office based physicians assess thromboembolic risk.

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Nonadherence in Outpatient Thrombosis Prophylaxis with Low Molecular Weight Heparins after Major Orthopaedic Surgery

Abstract: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.

Cited by 43 publications

References 45 publications

Worldwide adherence to ACCP guidelines for thromboprophylaxis after major orthopedic surgery: A systematic review of the literature and meta-analysis

Worldwide adherence to ACCP guidelines for thromboprophylaxis after major orthopedic surgery: A systematic review of the literature and meta-analysis

Toward Identifying the Causes and Combinations of Causes Increasing the Risks of Nonadherence to Medical Regimens: Combined Results of Two German Self-Report Surveys

Continuation of venous thromboembolism prophylaxis after hospital discharge into the outpatient setting: the ACCEPT study

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