Nonengineered Fungus Provides a Shortcut from Cellulose to Bulk Erythro-isocitric Acid
Ivan Schlembach,
Bettina Bardl,
Lars Regestein
et al.
Abstract:The biotechnological valorization of renewable lignocellulose into chemical building blocks, such as organic acids, has been defined as a cornerstone for the transition to a sustainable bioeconomy. Yet, large-scale commercialization is hampered by a complex multistage process. Therefore, the integration of cellulase production, cellulose hydrolysis, and product fermentation into a single step is considered a breakthrough technology offering a real economic advantage. Here, we demonstrate that the natural fungu… Show more
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