Noninvasive pacemaker stress echocardiography for diagnosis of coronary artery disease

Picaño, Eugenio; Alaimo, Andrea; Chubuchny, Vlad; Płońska, Edyta; Baldo, Vittorio; Baldini, U; Pauletti, M; Perticucci, R; Fonseca, Lucas; Villarraga, Hector R.; C, Emanuelli; Miracapillo, Gennaro; Hoffmann, Enrico; Nes, Michele De

doi:10.1016/s0735-1097(02)02157-5

Cited by 55 publications

(38 citation statements)

References 23 publications

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“…Ивабрадин -препарат, уменьшающий частоту сердечных сокращений, кото-рый селективно подавляет ток I (f) водителя ритма в синусовом узле и, как следствие, снижает потреб-ность миокарда в кислороде, не влияя при этом на инотропную функцию сердца или АД [307]. Он был разрешен к применению Европейским агент-ством по лекарственным средствам (EMA) для лече-ния хронической стабильной стенокардии у пациен-тов с непереносимостью β-адреноблокаторов или неадекватным контролем на фоне их применения, у которых частота сердечных сокращений превышает 60 уд/мин (при синусовом ритме) [220,307]. Ивабра-дин был столь же эффективным, как и атенолол или амлодипин, у пациентов со стабильной ИБС; добав-ление ивабрадина 7,5 мг 2 раза в сутки к терапии атенололом привело к лучшему контролю частоты сердечных сокращений и симптомов стенокардии [307,308].…”

Section: • не-дигидропиридиновые (брадикардитические) антагонисты калunclassified

2013 Esc Guidelines on the Management of Stable Coronary Artery Disease

Montalescot

Sechtem²,

Achenbach³

et al. 2014

Russ J Cardiol

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Section: • не-дигидропиридиновые (брадикардитические) антагонисты калunclassified

2013 Esc Guidelines on the Management of Stable Coronary Artery Disease

Montalescot

Sechtem²,

Achenbach³

et al. 2014

Russ J Cardiol

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“…Benchimol et al [10 ]reported a sensitivity of 77% and specificity of 90% in 25 patients. Picano et al [11] performed PASE in 46 patients. The sensitivity was 85% with 88% specificity.…”

Section: Discussionmentioning

confidence: 99%

Accuracy and Long-Term Prognostic Value of Pacing Stress Echocardiography Compared with Dipyridamole Tl<sup>201</sup> Emission Computed Tomography in Patients with a Permanent Pacemaker and Known or Suspected Coronary Artery Disease

Shimoni¹,

Goland²,

Livshitz³

et al. 2010

Cardiology

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Objectives: Myocardial ischemia is difficult to assess by noninvasive methods in patients with a permanent pacemaker. Pacing stress echocardiography (PASE) has been used successfully in the detection of coronary artery disease (CAD). However, there are no data comparing PASE and other methods. Methods: We compared agreement and accuracy of PASE and radionuclide tomography (SPECT) in detecting CAD in 58 patients, mean age 75 ± 7 years, with a permanent pacemaker and known or suspected CAD. Thirty-nine patients underwent coronary angiography. The prognostic value of these tests was determined by prediction of cardiac events and cardiac death. Results: PASE and SPECT were positive in 39 and 43 patients, respectively. The agreement between the tests was 75%; kappa value 0.64. The sensitivity was 87 and 96% and the specificity 78 and 57%, respectively. With median follow-up of 51 months, there were 24 cardiac events and 8 cardiac deaths. Multivariable analysis determined that positive PASE was the only independent predictive factor associated with cardiac events and cardiac death. Conclusions: PASE is a feasible and effective method for detection of significant CAD in patients with permanent-pacemaker and allows effective risk stratification. PASE merits further study in larger prospective comparative studies.

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“…Picano et al 5) evaluated the feasibility, safety and diagnostic accuracy of pacemaker stress echocardiography in 46 consecutive patients with a permanent pacemaker and they had suspected or known coronary artery disease. The sensitivity for detecting significant coronary artery disease was 70%, the specificity was 90% and the accuracy was 78%.…”

Section: Discussionmentioning

confidence: 99%

“…3) Noninvasive pacemaker stress echocardiography (PASE) can increase the heart rate and induce myocardial ischemia in these patients. 4,5) We evaluated the diagnostic accuracy of performing noninvasive PASE as a screening test for coronary artery disease in patients with atypical angina and a permanent pacemaker.…”

Section: Introductionmentioning

confidence: 99%

Noninvasive Pacemaker Stress Echocardiography as a Screening Test for Coronary Artery Disease in Patients With Atypical Angina and Permanent Pacemaker

et al. 2008

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Background and Objectives: Making the noninvasive diagnosis of coronary artery disease in patients with a permanent pacemaker is difficult because of the inability to interpret electrocardiograms and the low specificity of perfusion scintigraphy. We evaluated the diagnostic accuracy of noninvasive pacemaker stress echocardiography (PASE) as a screening test for coronary artery disease in patients with atypical angina and a permanent pacemaker. Subjects and Methods: This a prospective study, and transthoracic stress-pacing echocardiography was performed on 15 patients (9 men and 6 women; age, mean age: 71.1±11.0 years) with atypical angina and a permanent pacemaker. All the patients underwent noninvasive pacemaker-stress echocardiography by external programming (pacing the heart rate up to 150 beats per minute). Coronary angiography was performed on the 8 patients with positive PASE results. Significant coronary artery disease was defined as ≥70% stenosis in at least one major coronary artery. Results: The echocardiographic images were interpretable for all the patients. No significant side effects were observed. The left ventricular systolic function was preserved in all the patients (left ventricular ejection fraction; 63.5±8%). Only 5 (62.5%) of 8 patients showed significant coronary artery disease, as documented by coronary angiography. Conclusion: Noninvasive PASE is a simple, rapid, safe and diagnostically efficient test for detecting coronary artery disease in patients with atypical angina and a permanent pacemaker. Larger studies are necessary to validate our findings.

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Noninvasive pacemaker stress echocardiography for diagnosis of coronary artery disease

Abstract: Noninvasive PASE is a simple, rapid, safe, and diagnostically efficient option for patients with permanent PM and suspected or known CAD.

Cited by 55 publications

References 23 publications

2013 Esc Guidelines on the Management of Stable Coronary Artery Disease

2013 Esc Guidelines on the Management of Stable Coronary Artery Disease

Accuracy and Long-Term Prognostic Value of Pacing Stress Echocardiography Compared with Dipyridamole Tl<sup>201</sup> Emission Computed Tomography in Patients with a Permanent Pacemaker and Known or Suspected Coronary Artery Disease

Noninvasive Pacemaker Stress Echocardiography as a Screening Test for Coronary Artery Disease in Patients With Atypical Angina and Permanent Pacemaker

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