Nonionic nontoxic antimicrobial polymers: indole-grafted poly(vinyl alcohol) with pendant alkyl or ether groups

Abstract

A series of new nonionic antimicrobial polymers with polyvinyl alcohol (PVA) backbone grafted with indole units and different hydrophobic alkyl or ether groups were synthesized by facile esterification. The chemical...

Biocompatible non-leachable antimicrobial polymers with a nonionic hyperbranched backbone and phenolic terminal units

“…The cytotoxicity to MG-63 osteoblast-like human cells of the obtained monomer 3 and HBPs were evaluated using a standard MTT assay. 23,96 As illustrated in Fig. 10, the cell viability of monomer 3 at 100, 500 and 1000 mg mL À1 were less than 40% (21, 24, and 31% respectively), indicating its significant toxicity to the tested cells.…”

Mitsunobu Functionalization of Poly(vinyl alcohol) Derivatives†

“…[ 4 ] Using the same acetalation reactions, various cross‐linked networks and hydrogels can be prepared from PVA. [ 5‐11 ] In addition, oxidation [ 12 ] and esterification [ 13 ] can also be performed on PVAs to install various functional groups. The functionalization “beltline” from PVAc to PVA then to PVB gives rise to three commercial polymers with unique properties and applications.…”

Eco-Friendly Cellulose-Based Nonionic Antimicrobial Polymers with Excellent Biocompatibility, Nonleachability, and Polymer Miscibility

“…Unlike traditional ionic antimicrobial agents, nonionic antimicrobial agents interact with bacterial cell films through hydrogen-bonding and hydrophobic or dipole–dipole interactions to achieve the inhibition of bacterial population sensing behavior and sustained bactericidal activity. , Indole derivatives are small, nonionic molecules of plant origin that are abundant in nature and household waste. They are often used as natural antibiotics with antimicrobial properties in various high-performance packaging and textile applications, such as indole-based polyesters, polyketones, and polyurethanes. − …”