In this paper we provide an abstract aproach to the study of classes of multiple summing multilinear operators between Banach spaces. The main purpose is unify the study of several known classes and results, for example multiple (p, q 1 , . . . , q n )summing operators, multiple mixing (s, q, p)-summing operators and multiple strong (s, q, p)-mixing summing operators. We also define new class of multiple summing multilinear operator that are particular cases of our construction and, therefore, satisfy the results proved in the paper. * joilsonor@ufba.br † Supported by CAPES doctoral scholarship. 2010 Mathematics Subject Classification: 46B45, 47L22, 40Bxx.