Nonmuscle-invasive and Muscle-invasive Urinary Bladder Cancer

Wang, Yanchun; Li, Zhen; Meng, Xiaoyan; Hu, Xuemei; Shen, Yaqi; Morelli, John N.; Lin, Hui; Zhang, Zhongping; Hu, Daoyu

doi:10.1097/md.0000000000002951

Cited by 14 publications

(9 citation statements)

References 26 publications

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“…Similar results were also noted in abdominal organs. Peng et al [ 8 ] and Wang et al [ 10 ] reported that image quality was significantly higher for r-FOV DWI images than the f-FOV DWI images in both rectal and urinary bladder tumors. Similar results were obtained in prostate tumor by Tamada et al [ 11 ] The r-FOW DWI sequence allowed the edge of the gallbladder wall and the structure of the tissue to be displayed more clearly, and it is easier to detect small lesions.…”

Section: Discussionmentioning

confidence: 99%

Gallbladder carcinoma: an initial clinical experience of reduced field-of-view diffusion-weighted MRI

Zou

Wang

et al. 2020

Cancer Imaging

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Background: The purpose of this study is to compare the diagnostic value, imaging quality and apparent diffusion coefficient (ADC) value of reduced field-of-view diffusion-weight imaging (r-FOV DWI) and full field-of-view diffusion-weight imaging (f-FOV DWI) in patients with gallbladder carcinoma and other lesions of gallbladder. Methods: Two hundred ninety-six patients with gallbladder diseases underwent both r-FOV DWI and f-FOV DWI on a 3.0 T MRI scanner. Two radiologists assessed subjective image quality parameters independently. The Wilcoxon signed-rank test was used to compare subjective qualitative image score. Objective quality values and the mean ADC values were analyzed by paired t-test. The correlation between pathological results and mean ADC value were estimated using Spearman rank correlation analysis. Results: The CNR value (10.23 ± 2.92) and image quality score (13.84 ± 1.07) of r-FOV DWI were significantly higher than those of f-FOV DWI (5.24 ± 1.29 P<0.001; 10.41 ± 1.11 P<0.001). There was no significant difference between mean ADC values of the two DWI sequences for all three groups (Group 1, chronic cholecystitis; Group 2, benign lesions of gallbladder; Group 3, gallbladder carcinoma. P = 0.239, 0.974 and 0.226 respectively). For both DWI sequences, the mean ADC values were the highest in the group of cholecystitis and the lowest in the group of gallbladder carcinoma (2.49 ± 0.14 vs 1.49 ± 0.12; 2.50 ± 0.14 vs 1.50 ± 0.13, for f-FOV and r-FOV respectively), the differences among groups were statistically significant (P<0.01). The mean ADC values for both DWI sequences were negatively correlated with the group number, which increased with the malignant tendency of lesions (r = − 0.892, P<0.01; r = − 0.913, P<0.01 for f-FOV and r-FOV respectively). Conclusion: Reduced Field-of-view Diffusion-weighted MRI is a good tool to diagnosis the gallbladder carcinoma, with better image quality and without affecting ADC values.

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Section: Discussionmentioning

confidence: 99%

Gallbladder carcinoma: an initial clinical experience of reduced field-of-view diffusion-weighted MRI

Zou

Wang

et al. 2020

Cancer Imaging

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“…When discordance between the T2WI and DCE exists, high-quality DW images should be considered as the predominant sequence to maximize the diagnostic performance. 26,28 In this study, all exams were performed on a 3.0 T MRI system and were acquired with high-resolution images, 22,29,30 which were essential for the scoring. Moreover, the application of bi-planar rFOV DWI sequence ensured that the tumor base was visible.…”

Section: Discussionmentioning

confidence: 99%

“…In this study, all exams were performed on a 3.0 T MRI system and were acquired with high‐resolution images, 22,29,30 which were essential for the scoring. Moreover, the application of bi‐planar rFOV DWI sequence ensured that the tumor base was visible 22 .…”

Section: Discussionmentioning

confidence: 99%

Accuracy and Challenges in the Vesical Imaging‐Reporting and Data System for Staging Bladder Cancer

Meng

Wang

et al. 2022

Magnetic Resonance Imaging

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BackgroundThe Vesical Imaging‐Reporting and Data System (VI‐RADS) scoring system has been widely used to stage bladder cancer (BCa) since 2018.PurposeTo describe the characteristics of cases with discordant T2‐weighted imaging (T2WI) and diffusion‐weighted imaging (DWI) scores in patients with BCa and further verify the accuracy of the VI‐RADS scoring system and the necessity of dynamic contrast‐enhanced (DCE) sequence.Study TypeRetrospective.SubjectsA total of 106 patients (include 16.5% female) with bladder cancer.SequenceT2WI (fast spin echo), DWI (echo planer imaging), and DCE (gradient echo).AssessmentSome cases are difficult to score according to the system, mainly when the T2WI (category 4) and DWI (category 2) sequence scores are discordant, termed the discordant group below. The complementary group will be termed concordant group. Each MRI sequence was reviewed respectively according to the 5‐point VI‐RADS scoring system by three observers. The diagnostic ability of sequences for evaluating muscle invasion by BCa was calculated using histopathology as the reference standards.Statistical TestsReceiver operating characteristic (ROC) curve, DeLong test, intraclass correlation coefficient. A P value of 0.05 or less was considered statistically significant.ResultsFourteen cases (13.2%) had discordant VI‐RADS scoring system. In the discordant group, the area under the ROC curve (AUC) of DCE was 0.875, while the T2WI and DWI showed limited diagnostic performance (AUCs = 0.50). In the concordant group, there was no significant difference in diagnostic efficacy between the overall VI‐RADS (AUC: 0.950) and the combination of T2WI and DWI (AUC: 0.946) (P = 0.56). Among all patients, the AUC of overall VIRADS was 0.939 with a 3 or greater cutoff value.Data conclusionThe DCE was crucial in the discordant group for evaluating muscle‐invasiveness, while DCE may not be necessary for the concordant group. The VI‐RADS scoring system performed with overall good diagnostic performance in evaluating muscle‐invasiveness in BCa patients.Evidence Level4Technical EfficacyStage 3

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“…Zoomed DWI is one of techniques of rFOV DWI sequence. A few reports of rFOV DWI sequence for bladder cancer have been published [ 9 – 11 ], and the good image quality or superiority for diagnosis of the differentiation between NMIBC and MIBC of bladder cancer using rFOV DWI sequence were mentioned in these reports. If the rFOV DWI sequence is better than the conventional DWI using VI-RADS for the distinction of NMIBC and MIBC, the superiority of rFOV DWI sequence might be firmer.…”

Section: Discussionmentioning

confidence: 99%

“…With Zoomed DWI, the ability to discriminate NMIBC and MIBC may be better than with conventional DWI. Recently, a few reports of rFOV sequence for bladder cancer have been published [ 9 – 11 ]. However, there have been few reports evaluating the diagnostic ability of the differentiation between NMIBC and MIBC of bladder cancer on rFOV DWI sequence using VI-RADS.…”

Section: Introductionmentioning

confidence: 99%

Comparison of reduced field-of-view DWI and full field-of view DWI for the differentiation between non-muscle invasive bladder cancer and muscle invasive bladder cancer using VI-RADS

et al. 2022

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Purpose To evaluate whether reduced field-of-view (rFOV) DWI sequence improves the differentiation between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) using VI-RADS. Material and methods Eighty-nine patients underwent bladder MRI with full field-of-view (fFOV) DWI and rFOV DWI sequence. Images were independently evaluated by 2 radiologists. The sensitivities, specificities, accuracies, and areas under the curve (AUCs) for the differentiation between NMIBC and MIBC with fFOV DWI and with rFOV DWI sequence were calculated using VI-RADS. Apparent diffusion coefficients (ADC) values were measured for each patient and averaged. Results The sensitivity, specificity, accuracy, and AUC by reader 1 were 92%, 78%, 82% and 0.905 with fFOV DWI, and 92%, 86%, 88% and 0.916 with rFOV DWI sequence, respectively. The sensitivity, specificity, accuracy and AUC by reader 2 were 96%, 76%, 82% and 0.900 with conventional DWI, and 96%, 81%, 85% and 0.907 with rFOV DWI sequence, respectively. The specificity and accuracy of reader 1 were significantly better with rFOV DWI sequence than with fFOV DWI, in contrast there was no significant difference for the others. The average of ADC values of fFOV DWI and rFOV DWI sequence were 1.004×10−6 mm2/s and 1.003×10−6 mm2/s, respectively. Conclusion The diagnostic ability of rFOV DWI sequence may be better than that of fFOV DWI using VI-RADS for the differentiation between NMIBC and MIBC regardless of image-reading experience, it is controversial.

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Nonmuscle-invasive and Muscle-invasive Urinary Bladder Cancer

Cited by 14 publications

References 26 publications

Gallbladder carcinoma: an initial clinical experience of reduced field-of-view diffusion-weighted MRI

Gallbladder carcinoma: an initial clinical experience of reduced field-of-view diffusion-weighted MRI

Accuracy and Challenges in the Vesical Imaging‐Reporting and Data System for Staging Bladder Cancer

Comparison of reduced field-of-view DWI and full field-of view DWI for the differentiation between non-muscle invasive bladder cancer and muscle invasive bladder cancer using VI-RADS

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