Nonsurgical Management of Hyperhidrosis

Gee, Sarah N.; Yamauchi, Paul S.

doi:10.1016/j.thorsurg.2008.01.003

Cited by 37 publications

(59 citation statements)

References 80 publications

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“…Palmoplantar bölgedeki terleme serebral korteks tarafından kontrol edilir (10). Bu nedenle, palmoplantar hiperhidrozda egzersiz veya ortam sıcaklığının yüksekliğinden çok, korku, heyecan ve stres gibi emosyonel uyaranlar rol oynamaktadır (1,3). Aksiller bölgedeki terlemeyi ise hem emosyonel hem de termoregulatuvar uyaranlar etkilemektedir (6).…”

Section: Hiperhidroz Ve Başlıca Tedavi Seçenekleri Etiyolojiunclassified

“…Patogenezi tam olarak aydınlatılamamış olan primer hiperhidrozlu hastaların çoğunda ekrin ter bezlerinin morfolojik olarak normal olduğu, ancak anormal fonksiyon gösterdiği bulunmuştur (11). Sempatik sinir sisteminin bilinmeyen bir nedene bağlı olarak aşırı çalışması en çok suçlanan mekanizmadır (3,12). Ayrıca, ekrin ter bezlerinin emosyonel strese ve/veya fiziksel aktivite ve ısı gibi tüm sempatik uyaranlara karşı yanıtı-nın arttığı ileri sürülmüştür (3,13).…”

Section: Hiperhidroz Ve Başlıca Tedavi Seçenekleri Etiyolojiunclassified

“…Hiperhidroz, ekrin ter bezlerinin hiperaktivitesine bağlı olarak deri yüzeyine vücudun normal fizyolojik ihtiyacından daha fazla miktarda ter salgılanması ile karakterize bir hastalıktır (1)(2)(3). İnsidansı tam olarak bilinmemekle birlikte, yapılan bir çalışmada genel popülasyonun %1'inde, diğer bir çalışmada %2.8'inde görüldüğü bulunmuştur (4,5).…”

unclassified

“…Etkilenen kişilerde fiziksel ve psikososyal pek çok rahatsızlığa yol açması nedeniyle etkin bir şekilde tedavi edilmelidir (1)(2)(3). Sekonder hiperhidrozda tedavi öncelikle altta yatan hastalığa yönelik olmalıdır (2).…”

unclassified

“…Sekonder hiperhidrozda tedavi öncelikle altta yatan hastalığa yönelik olmalıdır (2). Primer hiperhidrozun tedavisi ise patofizyolojisinin tam olarak aydınlatılama-ması nedeniyle zordur (1)(2)(3)6).…”

unclassified

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Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Özcan¹,

Güleç²

2011

Turk J Dermatol

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ÖzetPrimer hiperhidroz sebebi bilinmeyen, en sık palmar, plantar ve aksiller bölgede ortaya çıkan, çoğunlukla bilateral ve simetrik olan aşırı terleme ile karakterizedir. Etkilenen bireylerde fiziksel rahatsızlıklar ve psikososyal güçlüklere yol açtığı için etkin bir şekilde tedavi edilmelidir. Ancak, patofizyolojisinin tam olarak anlaşılmaması nedeniyle tedavisi zordur. Topikal ve sistemik ajanlar ile cerrahi ve cerrahi olmayan invaziv teknikler gibi çeşitli seçenekler bulunmaktadır. İyontoforez, iyonize maddelerin elektrik akımı aracılığıyla yüzey dokulara uygulanması işlemidir. Primer hiperhidrozda invaziv olmayan, güvenli, iyi tolere edilen, etkili ve uzun dönem yan etkiler ile kompansatuvar hiperhidroza neden olmayan bir tedavi yöntemidir. Şiddetli palmar ve/veya plantar hiperhidrozda ve topikal tedaviye yanıt vermeyen orta şiddetteki olgularda ilk tedavi seçeneği olarak önerilmektedir. Aksiller hiperhidrozda ise etkinliği düşüktür ve kullanımı pratik değildir. Zaman alıcı olması ve idame tedavisinin gerekliliği ise en önemli dezavantajlarıdır. Bu makalede, hiperhidroz ve başlıca tedavi seçenekleri, iyontoforezin primer hiperhidroz tedavisindeki endikasyonları, etki mekanizması, tedavi protokolü ile yöntemi, yan etkileri ve kontrendikasyonları derlenmiştir. AbstractPrimary hyperhidrosis is characterized by excessive sweating of unknown cause which most commonly involves the palms, soles, and axillae in a bilateral and symmetrical fashion. Since it leads to physical discomfort and psychosocial difficulties in the affected individuals, it should be treated effectively. However, treatment can be challenging as its pathophysiology is poorly understood. There are several treatment options, including topical or systemic medications and surgical or non-surgical invasive techniques. Iontophoresis is the introduction of ionized substances into the surface tissues by means of an electric current. It is a non-invasive, safe, well tolerated, and effective treatment method for primary hyperhidrosis without long-term adverse effects and compensatory hyperhidrosis. Iontophoresis is suggested as a first-line therapy in severe palmoplantar hyperhidrosis and second-line therapy in milder cases that are unresponsive to topical treatments. In axillary hyperhidrosis it is less effective and not practical to use. Being time consuming and requiring maintenance therapy are its most important disadvantages. In this article, hyperhidrosis and the principal treatment options, the indications of iontophoresis for the treatment of primary hyperhidrosis, its mechanism of action, treatment protocol and procedure, adverse effects, and contraindications are reviewed. (Turk J Dermatol 2011; 5: 5-12)

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Section: Hiperhidroz Ve Başlıca Tedavi Seçenekleri Etiyolojiunclassified

unclassified

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Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Özcan¹,

Güleç²

2011

Turk J Dermatol

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Aluminium in cosmetics and personal care products

Sanajou

Şahin

Baydar

2021

J of Applied Toxicology

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Usage of inorganic ingredients like aluminium salts in cosmetics and personal care products has been a concern for producers and consumers. Although aluminium is used to treat hyperhidrosis, some worries have been raised about aluminium's role in breast cancer, breast cyst and Alzheimer's disease. The human population is exposed to aluminium from vaccines, diet, and drinking water, but the frequent use of aluminium‐based cosmetics might add additional local exposure. This paper reviews literature to determine if aluminium‐based products may pose potential harm to the body. The dermal absorption of aluminium is not widely understood. It is not yet known whether aluminium can travel from the skin to brain to cause Alzheimer's disease. Aluminium may cause gene instability, alter gene expression or enhance oxidative stress, but the carcinogenicity of aluminium has not been proved yet. Until now, epidemiological researches were based on oral information, which lacks consistency, and the results are conflicting. Future studies should target real‐life‐based long‐time exposure to antiperspirants and other aluminium‐containing cosmetics and personal care products.

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Reversibility of hyperhidrosis post axillary depilatory laser

et al. 2013

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Hyperhidrosis and bromhidrosis were lately reported as novel side effects of laser-assisted removal of axillary hair. The goal of our study was to evaluate the reversibility of these two side effects. An observational, single-center cohort study included over a 30-month screening period 30 patients with newly reported hyperhidrosis and/or bromhidrosis related to axillary depilatory laser. After 26 weeks of follow-up, each patient was assessed for spontaneous reversibility. A 12-week duration treatment with topical aluminum chloride was evaluated in patients with persisting hyperhidrosis. Hyperhidrosis was assessed using the Hyperhidrosis Disease Severity Scale (HDSS). Spontaneous reversibility was observed in 20% of patients. In total, 23 out of 30 patients recovered normal axillary transpiration either spontaneously or after treatment. Mean HDSS score was significantly lower in the treated group. It appears that axillary hyperhidrosis and bromhidrosis, secondary to laser depilation, reverse either spontaneously or after using topical antiperspirant.

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Nonsurgical Management of Hyperhidrosis

Cited by 37 publications

References 80 publications

Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Aluminium in cosmetics and personal care products

Reversibility of hyperhidrosis post axillary depilatory laser

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