Normal limits of the spatial QRS-T angle and ventricular gradient in 12-lead electrocardiograms of young adults: dependence on sex and heart rate

Scherptong, Roderick W.C.; Henkens, Ivo R.; Man, Sumche; Cessie, Saskia le; Vliegen, Hubert W.; Draisma, Harmen H.M.; Maan, Arie C.; Schalij, Martin J.; Swenne, Cees A.

doi:10.1016/j.jelectrocard.2008.07.006

Cited by 83 publications

(78 citation statements)

References 26 publications

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“…The upper limits of normal obtained for Caucasians in this study for the age-group 18-29 years were 108° for females and 127° for males. These are in line with those reported by Sherptong et al [13] in their study on a population of students in the same age-group in Leiden, Netherlands, i.e. 116° for females and 130° for males.…”

Section: Discussionsupporting

confidence: 92%

Comparison of Spatial QRS:T Angle in Different Healthy Racial Groups

Clark

Macfarlane

2016

2016 Computing in Cardiology Conference (CinC)

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Section: Discussionsupporting

confidence: 92%

Comparison of Spatial QRS:T Angle in Different Healthy Racial Groups

Clark

Macfarlane

2016

2016 Computing in Cardiology Conference (CinC)

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“…26 Full details on the computation method and LEADS based values of vector characteristics in healthy subjects have been extensively described earlier. 27 In short, the software converts the standard ECG into a vectorcardiogram and computes the 3D orientation of the QRS-and T-axes. Thereafter, the QRS-T angle is calculated in the plane formed by the QRS-and T-axes, the spatial QRS-T angle.…”

Section: Ecg Analysismentioning

confidence: 99%

“…As a consequence of the balanced regulation of electric activation and recovery of the ventricles, a narrow QRS-T angle is generally observed in healthy individuals. 27 Ventricular scar or residual ischemia, which is the arrhythmic substrate in ischemic cardiomyopathy, causes an imbalance of this process, sometimes referred to as electric heterogeneity or discordance of depolarization and repolarization. 30 Vectorcardiographically, these alterations in cardiac electrophysiology become, among others, apparent through directional changes of the QRS and T vectors and consequent widening of the QRS-T angle.…”

Section: Risk Stratification With the Qrs-t Anglementioning

confidence: 99%

Predicting Ventricular Arrhythmias in Patients With Ischemic Heart Disease

Borleffs

Scherptong

Man

et al. 2009

Circ: Arrhythmia and Electrophysiology

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139

122

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Background-In patients with primary prevention implantable cardioverter-defibrillators (ICDs), the incidence of life-threatening ventricular arrhythmias resulting in ICD therapy is relatively low, prompting for better risk stratification. The aim of this study was to assess the value of the QRS-T angle for prediction of ICD therapy and mortality in primary prevention patients with ischemic heart disease. Methods and Results-ICD patients (nϭ412, 361 men; age, 63Ϯ11 years) with ischemic heart disease and a left ventricular ejection fraction Յ40% were included. After device implantation, the occurrence of appropriate ICD therapy and mortality was noted. A survival analysis was performed comparing patients with a planar QRS-T angle Յ90°( nϭ124, 30%) with patients with a planar QRS-T angle Ͼ90°before device implantation. Furthermore, patients with a spatial QRS-T angle Յ100°(nϭ56, 14%) were compared with patients with a spatial QRS-T angle Ͼ100°, before implantation. For patients with a planar QRS-T angle Ͼ90°as compared with Յ90°, the adjusted hazard ratio for the occurrence of appropriate device therapy was 2.4 (95% CI, 1.1 to 5.2); a spatial QRS-T angle Ͼ100°was associated with an adjusted hazard ratio of 7.3 (95% CI, 1.0 to 53.8). Furthermore, a spatial QRS-T angle Յ100°exhibited a positive predictive value of 98% (95% CI, 95 to 100) for the prediction of an appropriate therapy-free follow-up. Conclusions-A wide QRS-T angle is a strong predictor of appropriate device therapy in primary prevention ICD recipients with ischemic heart disease. Furthermore, a spatial QRS-T angle Յ100°might be of value in the identification of patients in whom, although currently indicated, ICD treatment should be reconsidered. (Circ Arrhythmia Electrophysiol. 2009;2:548-554.)

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“…Changes in the depolarization sequence as well as changes in the action potential duration are reflected in the SA [1]. Narrow SA angles indicate a normal relationship between ventricular depolarization and repolarization [2]. A widening of the SA is an indication of an abnormal relationship between ventricular depolarization and repolarization [2].…”

Section: Introductionmentioning

confidence: 99%

“…Narrow SA angles indicate a normal relationship between ventricular depolarization and repolarization [2]. A widening of the SA is an indication of an abnormal relationship between ventricular depolarization and repolarization [2]. The properties of the SA have previously been demonstrated to have clinical value in different applications [3,4].…”

Section: Introductionmentioning

confidence: 99%