Nosocomial Infections with Gentamicin-Resistant Staphylococcus aureus: Plasmid Analysis as an Epidemiologic Tool

Susceptibility to Antimicrobial Agents and Analysis of Plasmids in Gentamicin- And Methicillin-Resistant Staphylococcus Aureus From Dublin Hospitals

“…The MGRSA strains isolated in Dublin differ from similar S. aureus strains that have been reported from France, Australia, the UK and the USA (Soussy et al, 1975;Shanson et al, 1976;Crossley et al, 1979;McGowan et al, 1979;Price et al, 1980;Jaffe et al, 1982;Archer and Mayhall, 1983;Lyon et al, 1983;Naidoo et al, 1983;Townsend et al, 1983a) by invariably exhibiting chromosomal resistance to gentamicin. In strains reported from the USA, resistance to gentamicin is often encoded by large conjugative plasmids (Archer and Johnston, 1983;Forbes and Schaberg, 1983;McDonnell et al, 1983).…”

Molecular epidemiology of multiresistant Staphylococcus aureus in Australian hospitals

“…The value of plasmid analysis in the epidemiological study of nosocomial infection with S. aureus is well established (McGowan et al, 1979;El Solh et al, 1980;Locksley et a/., 1982). We have examined previously strains of antibiotic multiresistant S. aureus, isolated from patients in Melbourne hospitals, for the presence of resistance plasmids (Lyon et al, 1982;Lyon, May and Skurray, 1983).…”

Cryptic Plasmids in Hospital Isolates of Providencia Stuarti

“…It has been suggested that the plasmid content of a bacterial isolate may be a useful epidemiological marker (McGowan et al, 1979;Parisi and Hecht, 1980;Hughes et al, 1981;Sasarman et al, 1981;Riley and Cohen, 1982;Bezanson, Khakhria and Pagnutti, 1983). However, when an outbreak of hospital infection with Klebsiella aerogenes was investigated it was found that although all 56 examples of the epidemic strain, identical by capsular and klebecin typing, carried the same resistance plasmid, there was variation in the cryptic plasmid content of the isolates.…”

“…wt may not be identical (Farrar, 1983). Nonetheless, it has been shown that the plasmid profile of an isolate can be used as an epidemiological marker (McGowan et al, 1979).…”