Not Everything that is Hot on a Staging Bone Scan is Malignant: A Pictorial Review of Benign Causes of Increased Isotope Uptake

Moran, Dermot; O’Neill, Ailbhe C.; Heffernan, Eric J.; Skehan, Stephen J.

doi:10.1016/j.carj.2011.02.009

Cited by 2 publications

(2 citation statements)

References 13 publications

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“…However, larger lesions may demonstrate either increased or decreased uptake. [7] They may be erroneously labelled as metastases on bone scan in background of primary malignancy which have predilection for skeletal (lytic) metastases. In addition to post-external radiotherapy, haemangioma is also one of the causes of 'cold' vertebrae on skeletal scintigraphy.…”

Section: Discussionmentioning

confidence: 99%

Intraosseous Haemangiomas on Hybrid Imaging: A Pictorial Review

Razi

Bashir

Riaz

et al. 2016

J Cancer Allied Spec

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Osseous haemangiomas are benign skeletal tumours, usually identi ed as incidental ndings on different imaging modalities. Bone scan is the most frequent radionuclide procedure performed as metastatic workup in patients with various malignancies. Not every hotspot on a staging bone scan is malignant. Haemangiomas with variable degree of radiotracer uptake on technetium-99m (Tc-99m) bone scintigraphy may be falsely labelled as metastases in background of known malignancy. The addition of single-photon emission computed tomography computed tomography (SPECT-CT) enhances the specificity of bone scan which allows accurate detection and anatomical localisation of scintigraphic findings. We present a case series as pictorial review of osseous haemangiomas identi ed on Tc-99m methylene diphosphonate SPECT CT at our department. Key words: Haemangioma, methylene diphosphonate, bone scan, single-photon emission computed tomography- computed tomography

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Section: Discussionmentioning

confidence: 99%

Intraosseous Haemangiomas on Hybrid Imaging: A Pictorial Review

Razi

Bashir

Riaz

et al. 2016

J Cancer Allied Spec

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“…Increased isotope uptake is seen in several conditions where increased bone turnover occurs, including infection, cancers, and rheumatologic inflammatory conditions. 83 …”

Section: Isotope Bone Scansmentioning

confidence: 97%

The Pathophysiology, Diagnosis, and Management of Stress Fractures in Postmenopausal Women

Pegrum

Crisp

Padhiar

et al. 2012

The Physician and Sportsmedicine

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Optimal exercise programs should balance the beneficial effect of increasing bone mineral density through exercise with the detrimental effect of stress fractures. A useful algorithm is presented in this article to guide the clinician in the diagnosis and management of appropriate investigations and management of such injuries. This review article describes the pathophysiology and provides a review of the literature to determine the latest diagnostic and treatment strategies for this unique population.

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Not Everything that is Hot on a Staging Bone Scan is Malignant: A Pictorial Review of Benign Causes of Increased Isotope Uptake

Cited by 2 publications

References 13 publications

Intraosseous Haemangiomas on Hybrid Imaging: A Pictorial Review

Intraosseous Haemangiomas on Hybrid Imaging: A Pictorial Review

The Pathophysiology, Diagnosis, and Management of Stress Fractures in Postmenopausal Women

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