Notarization of Knowledge Retrieval from Biomedical Repositories Using Blockchain Technology

Mytis-Gkometh, Petros; Drosatos, George; Efraimidis, Pavlos S.; Kaldoudi, Eleni

doi:10.1007/978-981-10-7419-6_12

Cited by 33 publications

(15 citation statements)

References 12 publications

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“…Similarly, Nugent et al present their research in [60] in which they demonstrate how smart contracts on Ethereum blockchain platform can be used to improve data transparency in clinical trials. The Ethereum platform is also used to implement another blockchain-based solution that is proposed to notarize documents retrieved from biomedical databases [71].…”

Section: Resultsmentioning

confidence: 99%

Blockchain Technology in Healthcare: A Systematic Review

2019

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Since blockchain was introduced through Bitcoin, research has been ongoing to extend its applications to non-financial use cases. Healthcare is one industry in which blockchain is expected to have significant impacts. Research in this area is relatively new but growing rapidly; so, health informatics researchers and practitioners are always struggling to keep pace with research progress in this area. This paper reports on a systematic review of the ongoing research in the application of blockchain technology in healthcare. The research methodology is based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and a systematic mapping study process, in which a well-designed search protocol is used to search four scientific databases, to identify, extract and analyze all relevant publications. The review shows that a number of studies have proposed different use cases for the application of blockchain in healthcare; however, there is a lack of adequate prototype implementations and studies to characterize the effectiveness of these proposed use cases. The review further highlights the state-of-the-art in the development of blockchain applications for healthcare, their limitations and the areas for future research. To this end, therefore, there is still the need for more research to better understand, characterize and evaluate the utility of blockchain in healthcare.

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Section: Resultsmentioning

confidence: 99%

Blockchain Technology in Healthcare: A Systematic Review

2019

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“…[45]2018ConferenceHealth recordsArchitectureLiu W. [46]2017ConferenceHealth recordsProposalLightGray Mangesius P. [47]2018ConferenceHealth recordsArchitectureMense A. [48]2018ConferenceHealth recordsImplementationLightGray Mytis-Gkometh P. [49]2018ConferenceBiomedical databasesImplementationNugent T. [50]2016JournalClinical trialsImplementationLightGray Patel V. [51]2018JournalHealth recordsArchitectureRoehrs A. [52]2017JournalHealth recordsArchitectureSaravanan M. [53]2017ConferenceWearables & embeddedImplementationLightGray Staffa M. [54]2018JournalHealth recordsArchitectureTseng J.…”

Section: Resultsmentioning

confidence: 99%

“…Another contribution to biomedical research considers safeguarding researcher transactions with reference biomedical databases that hold continually submitted and updated scientific evidence (including clinical registries, pharmaceuticals, metabolomics and other omics, and publications). Blockchain technology has been proposed to provide integrity and non-repudiation for reference database queries and respective results [49], and versioning of time evolving database query results [42]. In all these applications, blockchain is employed as a distributed, tamper proof ledger of research activities on specific data, thus ensuring integrity, immutability and non-repudiation of research course.…”

Section: Discussionmentioning

confidence: 99%

Blockchain Applications in the Biomedical Domain: A Scoping Review

Drosatos

Kaldoudi

2019

Computational and Structural Biotechnology Journal

120

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Blockchain is a distributed, immutable ledger technology introduced as the enabling mechanism to support cryptocurrencies. Blockchain solutions are currently being proposed to address diverse problems in different domains. This paper presents a scoping review of the scientific literature to map the current research area of blockchain applications in the biomedical domain. The goal is to identify biomedical problems treated with blockchain technology, the level of maturity of respective approaches, types of biomedical data considered, blockchain features and functionalities exploited and blockchain technology frameworks used. The study follows the PRISMA-ScR methodology. Literature search was conducted on August 2018 and the systematic selection process identified 47 research articles for detailed study. Our findings show that the field is still in its infancy, with the majority of studies in the conceptual or architectural design phase; only one study reports real world demonstration and evaluation. Research is greatly focused on integration, integrity and access control of health records and related patient data. However, other diverse and interesting applications are emerging, addressing medical research, clinical trials, medicines supply chain, and medical insurance.

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“…This is likely due to its status as the first established blockchain platform supporting full fledged smart contracts. It's use cases span almost all sectors we looked at, including voting [71], taxation [74], and collaborative urban decisionmaking [5], [78] in government sector; research paper authoring collaboration [90], digital media rights protection [102] and lottery system [102] in education, culture, science and innovation sector; clinical trial process improvement [105], medical data sharing [110], [114], supply chain of drug [121] and food [124] in well-being, health and safety sector; collaborative business process [133], [134], product provenance [137], automated sales systems [139], and sharing economies [147], [148] in the economy sector; sustainable transportation [172] in the transportation sector; energy efficiency and peer-to-peer energy market [178]- [180], [183], [184], [187], [195], and electronic vehicle charging [204] in the energy sector; and building operation management access control [214] in the built environment sector. It should be noted that while Ethereum is a permissionless blockchain, most of the research prototypes are run on the test net or a separate private Ethereum network due to their early stage nature.…”

Section: ) Ethereummentioning

confidence: 99%

Blockchain for Cities—A Systematic Literature Review

2018

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Blockchain is considered one of the most disruptive technologies of our time. Numerous cities around the world are launching blockchain initiatives as part of the overall efforts toward shaping the urban future. However, the infancy stage of the blockchain industry leads to a severe gap between the knowledge we have and the actions urban policy makers are taking. This paper is an effort to narrow this rift. We provide a systematic literature review on concrete blockchain use cases proposed by the research community. At the macro-level, we discuss and organize use cases from 159 selected papers into nine sectors recognized as crucial for sustainable and smart urban future. At the micro-level, we identify a component-based framework and analyze the design and prototypes of blockchain systems studied in a subset of 71 papers. The high-level use case review allows us to illustrate the relationship between them and the four pillars of urban sustainability: social, economic, environmental, and governmental. The system level analysis helps us highlight interesting inconsistencies between well-known blockchain applicability decision rules and the approaches taken by the literature. We also offer two classification methodologies for blockchain use cases and elaborate on how they can be applied to stimulate cross-sector insights in the blockchain knowledge domain.INDEX TERMS Bitcoin, blockchain, computer networks, consensus, crypto token, distributed computing, Ethereum, Hyperledger Fabric, systematic literature review, smart city, smart contract, system analysis and design, peer-to-peer computing, urban sustainability, use case.

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Notarization of Knowledge Retrieval from Biomedical Repositories Using Blockchain Technology

Cited by 33 publications

References 12 publications

Blockchain Technology in Healthcare: A Systematic Review

Blockchain Technology in Healthcare: A Systematic Review

Blockchain Applications in the Biomedical Domain: A Scoping Review

Blockchain for Cities—A Systematic Literature Review

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