Note Free Flavonoid Aglycones from Inula montana

Bioassay-guided isolation and UHPLC-DAD-ESI-MS/MS quantification of potential anti-inflammatory phenolic compounds from flowers of Inula montana L

“…The spectroscopic data are shown in the Table 2. Reynaud and Lussignol, 1999 The compound 1 The chromatogram shows also three compounds (9, 10 and 11) with Rt 19.9, 19.2 and 20.5 min and parent ions m/z 331, 301 and 361 [M+H] + respectively. These compounds were confirmed to be 6-Hydroxykaempferol 3,7-dimethyl ether, Hispidulin and Chrysosplenol C, respectively by comparing their retention time and MS/MS data with those of the authentic substances (Garayev et al, 2017).…”

“…Previous phytochemical studies led to the isolation of flavonoid aglycones, sesquiterpene lactones and inositol derivatives (Garayev et al, 2017;Gonzalez Romero M.A. et al, 2001;Reynaud and Lussignol, 1999). Crude extracts and some purified constituents of I. montana demonstrated antioxidant, protozoocidal and anti-inflammatory activities (Garayev et al, 2017;Martín et al, 1998;Belyagoubi-Benhammou et al, 2014).…”

Ecophysiological and phytochemical characterization of wild populations of Inula montana L. (Asteraceae) in Southeastern France

“…Secondary metabolites (including sesquiterpene lactones) from Inula spp. have shown interesting biological activities such as antitumor, anti-inflammatory, antidiabetic, bactericidal, antimicrobial and antifungal activities, and these plants have also been used for tonics or diuretics (Reynaud and Lussignol, 1999;Seca et al, 2014).…”

“…This calcicolous and xerophilous plant can be locally abundant, particularly in the Garrigue-type lands (Gonzalez Romero et al, 2001;Girerd and Roux, 2011;Tela Botanica, 2016). In the south of France, I. montana was incorrectly called "Arnica" because it was used in old traditional medicine as an alternative drug to the well-known Arnica montana (Reynaud and Lussignol, 1999). Due to herbivory pressure, loss of habitat and the fact that it is mainly harvested from the wild, A. montana is cited in the Red List of Threatened Species (IUCN).…”

New sesquiterpene acid and inositol derivatives from Inula montana L.

“…Alcoholic and oil preparations of the flowering aerial parts of this plant are widely used in the traditional medicine of Provence (France) in the treatment of hematomas, as well as Arnica montana L. [4]. However, its phytochemical composition has been poorly investigated [5][6][7][8]. Only six sesquiterpene lactones, four free flavonoid aglycones and volatile composition have been reported in Inula montana L. until now [5,6].…”