Notes from the 2022 Folate, Vitamin B12, and One-Carbon Metabolism Conference

Abstract

Here, we present notes from the Folate, Vitamin B12, and One-Carbon Metabolism Conference organized by The Federation of American Societies for Experimental Biology (FASEB), held in Asheville, North Carolina, USA, 14–19 August 2022. We aim to share the most recent findings in the field with members of our scientific community who did not attend the meeting and who are interested in the research that was presented. The research described includes discussions of one-carbon metabolism at the biochemical and physiological levels and studies of the role of folate and B12 in development and in the adult, and from bacteria to mammals. Furthermore, the summarized studies address the role of one-carbon metabolism in disease, including COVID-19, neurodegeneration, and cancer.

Anencephaly in Slovakia and Czech Republic: embryogenesis, risk factors, epidemiology and preventative approaches

“…As FA plays a vital role in the development of NTDs, folate supplementation during gestation is recommended to reduce the risk of NTDs (123). Many excellent reviews on folate metabolism have appeared over the past decade (124)(125)(126)(127). There is an abnormal methylation caused by FA deficiency in NTDs.…”

Correction: Maynard et al. Notes from the 2022 Folate, Vitamin B12, and One-Carbon Metabolism Conference. Metabolites 2023, 13, 486

“…Thanks to feedback from several speakers, text was amended, and citations updated, in the original article [ 1 ]. A correction has been made to the following sections:…”