Pyrolysis of combustible municipal solid waste (MSW) is an environmentally friendly waste to energy process that produces an ecological bio-oil with a high-energy value. However, the challenge is to obtain the desired products in considerable quantities, of good quality, and at low cost. The present work objective is to evaluate combustible MSW potential available in Morocco and their recovery in bio-oil produced by pyrolysis. An evaluation was conducted based on the MSW characterization for different Moroccan cities. It shows that Morocco has significant potential in good quality RDF, having a high calorific value and a low environmental impact. The yield of bio-oil that can be produced by pyrolysis of the dry part of municipal waste for different Moroccan cities was estimated using an appropriate model. The average total bio-oil yield estimated for each city is 45 wt%. Besides, the high calorific value fraction of bio-oil derived from Moroccan RDF will cover ~45% of the country's fuel-oil needs.