Novel contrast-injection protocol for high-resolution abdominal CT-angiography: vascular visualization improvement with vasodilator

Hoshika, Minori; Yasui, Kotaro; Niguma, Takefumi; Kojima, Toru; Nishiyama, Norimi; Suzuki, Daisuke; Togami, Izumi

doi:10.1007/s00261-017-1163-y

Cited by 9 publications

(5 citation statements)

References 27 publications

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“…These authors found that there was a statistically significant difference in cross-sectional area between the nitrate and non-nitrate group at 10 cm distal to the origin of the superior mesenteric artery (11.6 ± 8.6 and 8.3 ± 3.2 mm 2 , respectively) despite the absence of a significant difference at the origin (34.6 ± 10.8 and 34.0 ± 5.5 mm 2 , respectively). The result by Hoshika et al 18 indicated that vessel dilatation due to sublingual was greater in the abdominal peripheral arteries than in large arteries, which is similar to what we have observed in our study. Similar positive effects of sublingual GTN on CTA performed before prostate artery embolization, which could combat the difficult vascular anatomy of the prostate gland, have also been reported 28 …”

Section: Discussionsupporting

confidence: 93%

“…We could not find any study evaluating the role of sublingual nitrate in peripheral CTA. However, a study by Hoshika et al 18 demonstrated that using sublingual nitrate before abdominal CTA improved visualization of peripheral abdominal vessels. These authors found that there was a statistically significant difference in cross-sectional area between the nitrate and non-nitrate group at 10 cm distal to the origin of the superior mesenteric artery (11.6 ± 8.6 and 8.3 ± 3.2 mm 2 , respectively) despite the absence of a significant difference at the origin (34.6 ± 10.8 and 34.0 ± 5.5 mm 2 , respectively).…”

Section: Discussionmentioning

confidence: 99%

“…Low-tube-voltage, high-tube-current CT techniques or full iterative reconstruction have also been suggested as aids to improve the resolution. 18,19 However, these techniques may require an overhaul in equipment and the extent of their positive effect has not yet been assessed for visualization of the infrapopliteal arterial tree.…”

mentioning

confidence: 99%

“…A lower tube voltage with a better match between the effective energy of the x-ray beam and the maximum absorption close to the K-edge of iodine also improves the contrast resolution. Low-tube-voltage, high-tube-current CT techniques or full iterative reconstruction have also been suggested as aids to improve the resolution 18,19 . However, these techniques may require an overhaul in equipment and the extent of their positive effect has not yet been assessed for visualization of the infrapopliteal arterial tree.…”

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confidence: 99%

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Can Sublingual Nitrate Improve Visualization of Lower Limb Arteries on Computed Tomography Angiography?

Gupta

Dixit

Prakash

et al. 2023

J Comput Assist Tomogr

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The aim of the study is to evaluate the role of sublingual nitrate in improving vessel visualization on peripheral computed tomography angiography (CTA).Methods: Fifty patients clinically diagnosed with peripheral arterial disease of the lower limb were prospectively included in this study: Twenty-five underwent CTA after sublingual nitrate administration (nitrate group) and 25 without (non-nitrate group). Two blinded observers qualitatively and quantitatively assessed the data thus generated. The mean luminal diameter, intraluminal attenuation, site, and percentage of stenosis were evaluated in all segments. Assessment of collateral visualization at sites of significant stenosis was also done.Results: Patients in the nitrate and non-nitrate groups were similar in age and sex characteristics ( P > 0.05).On subjective evaluation, there was significantly improved visualization of the femoropopliteal and tibioperoneal vasculature of the lower limb in the nitrate group compared with the non-nitrate group ( P < 0.05). Quantitative evaluation showed a statistically significant difference in the measured arterial diameters for all evaluated segments in the nitrate group versus the non-nitrate group ( P < 0.05). Intra-arterial attenuation was significantly greater for all segments in the nitrate group resulting in better contrast opacification in these studies. Collateral visualization around segments with more than 50% stenosis/occlusion was also better in the nitrate group. Conclusions:Our study suggests that nitrate administration before peripheral vascular CTA can improve visualization, especially in the distal segments by increasing the vessel diameter and intraluminal attenuation along with better delineation of the collateral circulation around stenotic areas. It may also improve the number of evaluable segments of vasculature in these angiographic studies.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Can Sublingual Nitrate Improve Visualization of Lower Limb Arteries on Computed Tomography Angiography?

Gupta

Dixit

Prakash

et al. 2023

J Comput Assist Tomogr

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“…The quantitative assessment was evaluated for 4 main coronary arteries which is LM, LCX, LAD and RCA. These assessment of image quality was determined by measuring 4 parameters which is signal intensity (SI), image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) (Kojima et al 2017). The measurements were performed on axial image of coronary arteries by one reviewer (radiographer).…”

Section: Quantitative Analysismentioning

confidence: 99%

Image Quality of Coronary CT Angiography (CCTA) using 640-slice Scanner: Qualitative and Quantitative Assessments of Coronary Arteries Visibility

Shamsul

Sabarudin

2020

JSKM

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The purpose of this study was to evaluate the image quality and diagnostic accuracy of coronary computed tomography angiography (CCTA) using 640-slice scanner. Advancement of multidetector computed tomography (MDCT) technology with higher spatial, temporal resolution, and increasing detector array have improved the image quality and diagnostic accuracy of CCTA. A total of 25 patients (12 men and 13 women) underwent CCTA examination was chosen and data was acquired by 640-slice scanner. All 16 segments of coronary arteries were evaluated by two reviewers using a 4-likert scale for qualitative assessment. In quantitative assessment, the evaluation of 4 main coronary arteries were analysed in terms of signal intensity (SI), image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). All 25 patients with a mean age of 52.88 ± 14.75 years old and body mass index (BMI) of 24.24 ± 3.28 kg/m 2 were analysed. In qualitative assessment, from the total of 400 segments, 379 segments (95%) had diagnostic value while 21 segments did not have diagnostic value, which means 5% artefact was detected. In quantitative assessment, there was no statistical differences in gender, race, and BMI (p>0.05). Overall evaluation showed that higher SI at the left main artery (LM) at 393.7 ± 47.19. Image noise was higher at right coronary artery (RCA) at 39.01 ± 13.97. SNR and CNR showed higher at left anterior descending (LAD) with 12.73 ± 5.17 and LM 9.14 ± 4.2, respectively. In conclusion, this study indicates that 640-slice MDCT has higher diagnostic value in CCTA examination with 95% vessel visibility with 5% artefact detection.

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CT Angiography of Mesenteric Circulation

Zhao,

Liu,

et al. 2024

Whole Body Computed Tomography Angiography

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Novel contrast-injection protocol for high-resolution abdominal CT-angiography: vascular visualization improvement with vasodilator

Abstract: Abdominal CTA using NTG improved visualization of the abdominal peripheral vessels. This improved arterial view may be beneficial for preoperative evaluation of the arterial anatomy.

Cited by 9 publications

References 27 publications

Can Sublingual Nitrate Improve Visualization of Lower Limb Arteries on Computed Tomography Angiography?

Can Sublingual Nitrate Improve Visualization of Lower Limb Arteries on Computed Tomography Angiography?

Image Quality of Coronary CT Angiography (CCTA) using 640-slice Scanner: Qualitative and Quantitative Assessments of Coronary Arteries Visibility

CT Angiography of Mesenteric Circulation

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