Novel e-nose for the discrimination of volatile organic biomarkers with an array of carbon nanotubes (CNT) conductive polymer nanocomposites (CPC) sensors

Surface modification of UF membranes with functionalized MWCNTs to control membrane fouling by NOM fractions

“…The membrane morphologies were determined using atomic force microscopy (AFM, Bioscope, Veeco, USA). Tapping mode was used to scan the membrane surface using a tip consisting of an etched single crystal of silicon (probe type of RTESP) [22,23]. The RTESP had a spring constant of 40 N/m, resonant frequency of 300 kHz, nominal tip radius of 8 nm.…”

Breath sensors for lung cancer diagnosis

“…Castro and co-workers reported an electronic nose design, consisting of five sensors that were made of hierarchically structured conductive polymer nanocomposites (CPC) (Castro et al, 2011). Five different polymer matrices and carbon nanotubes (CNT) lead to the conductive architecture of CPC, which helped to obtain the desired sensitivity and selectivity.…”

“…One order of magnitude improvement in LOD could be observed, due to chemical specific interactions, depending on the selected polymer in the CPC (Kang et al, 2010). This CPC transducer was tested with nine VOCs that were chosen among the lung cancer biomarkers in breath (Castro et al, 2011). Principal component analysis (PCA) was used as the pattern recognition tool, to separate vapor clusters.…”

“…Scheme of the chemo-resistive sensing device (a) and the chemo-resistive response (relative amplitude) of the sensor array in the presence of isopropanol solvent vapor (b)(Castro et al, 2011). Reprinted with permission from Elsevier.…”

Advances in the Early Detection of Lung Cancer using Analysis of Volatile Organic Compounds: From Imaging to Sensors

“…In 2011, Castro and co-workers optimized CPC sensors by varying the amount of carbon nanotubes as conductive filler with 5 different polymer matrices (Castro et al, 2011). Finally, high sensitivity and selectivity, as well as good rapidity and reproducibility, were obtained when the sensor array was exposed to 9 VOCs that were chosen among biomarkers for lung cancer detection.…”