Novel Endocuff-assisted Colonoscopy Significantly Increases the Polyp Detection Rate

Biecker, Erwin; Floer, Martin; Heinecke, Achim; Ströbel, Philipp; Böhme, Rita; Schepke, Michael; Meister, Tobias

doi:10.1097/mcg.0000000000000166

Cited by 105 publications

(132 citation statements)

References 23 publications

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“…In a recently published Swiss feasibility study with analysis of 104 EC-assisted colonoscopies, a good ADR of 47% was measured [76]. Biecker and Floer published 2 larger randomized controlled trials showing superiority of EndoCuff-assisted colonoscopy in terms of ADR [18,77]. The ADR significantly increased with the use of the EndoCuff compared to standard colonoscopy (35.4 vs. 20.7%, p < 0.0001).…”

Section: Technical Aspectsmentioning

confidence: 99%

“…One advantage of the EndoCuff compared to EndoRings might be the fact that the intubation of the terminal ileum can easily be performed. In all prospective studies available for EndoCuff, the rate of ileum intubation did not differ statistically compared to standard colonoscopy [18,77]. Thus, colonoscopy with EndoRings is therefore limited to the colon.…”

Section: Technical Aspectsmentioning

confidence: 99%

“…Data from Germany stress the likelihood of polyp detection in the left-sided colon [18], while data from the United States show advanced adenomas in the proximal colon in 20% of the cases [19]. …”

Section: Factors Influencing the Adrmentioning

confidence: 99%

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Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Floer

Meister²

2016

Digestion

Self Cite

238

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Background: The presence of colorectal adenomas is considered a major risk factor for colorectal cancer development. The implementation of screening colonoscopy programs in the Western world has led to a substantial reduction of colorectal cancer death. Many efforts have been made to reduce the adenoma miss rates by the application of new endoscopic devices and techniques for better adenoma visualization. Summary: This special review gives the readership an overview of current endoscopic innovations that can aid in the increase of the adenoma detection rate (ADR) during colonoscopy. These innovations include the use of devices like EndoCuff® and EndoRings® as well as new technical equipment like third-eye endoscope® and full-spectrum endoscopy (FUSE®). Key Message: Technical improvements and newly developed accessories are able to improve the ADR. However, additional costs and a willingness to invest into potentially expensive equipment might be necessary. Investigator-dependent skills remain the backbone in the ADR detection.

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Section: Technical Aspectsmentioning

confidence: 99%

Section: Technical Aspectsmentioning

confidence: 99%

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Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Floer

Meister²

2016

Digestion

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238

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“…Three studies including 2 prospective RCTs [7,8] and 1 retrospective study [9] , all from Germany describing the EC were included for the review. Six prospective RCTs, 1 each from Germany [10] , Hong Kong [11] , Netherlands [12] , US [13] , South Korea [14] , Australia [15] and 1 retrospective study from Hong Kong [16] describing the CAC were included for the review.…”

Section: Resultsmentioning

confidence: 99%

New Developments in Mechanical Enhancement of Colonoscopy: Cuffs, Caps and Rings

Jain

Sandhu

Singhal³

2016

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Background: Colorectal cancer (CRC) is a common cause of cancer-related deaths. Early detection of precursor lesions in the adenoma-carcinoma sequence via colonoscopy can decrease mortality from CRC. Summary: In this review article, we have summarized retrospective studies, prospective single center, multicenter studies and randomized controlled trials describing the efficacy of endocuff colonoscopy (EC), cap-assisted colonoscopy (CAC) and endorings colonoscopy (ERC). Indications, techniques, outcomes, limitations and complications reported are discussed. Key Message: Use of colonoscope with cap, cuff or rings attached to its distal tip has been shown to increase the polyp detection rate and adenoma detection rate, predominantly for the small polyps (<1 cm) and proximal colon location. Evidence is uniform for EC and ERC but not for CAC. Benefits of shorter cecum intubation time, improved cecum intubation rates and decreased pain scores during colonoscopy done with assistance of cuff or cap has potential to decrease the number of incomplete colonoscopy and increase overall patient satisfaction, thus improving follow-up. In the absence of any additional adverse events, EC, CAC and ERC have potential to enhance the benefits of colonoscopy.

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“…Endocuff has two rings of soft, flexible branches that are used to flatten the colonic folds while withdrawing the scope, making the area behing folds more visible. Its efficacy was evaluated in various studies, showing similar or higher adenoma detection rate (ADR) compared to standard colonoscopy [20,21].…”

Section: Introductionmentioning

confidence: 99%

Advances in endoscopic diagnosis of colorectal cancer

Čavlina¹,

Rustemović²

2017

Rad Hrvatske akademije znanosti i umjetnosti

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SummaryColorectal cancer (CRC) is the third most commonly diagnosed malignant tumor and the fourth leading cause of cancer death in the world. Since it is known that most of colorectal cancers arise from adenomatous polyps, screening programmes were developed in order to improve detection of polyps and early diagnosis of carcinoma. Colonoscopy is the gold standard for diagnosis of CRC. Because of its high adenoma missing rates and lower ability to differentiate between benign and malignant lesions novel techniques are being developed in order to improve mucosal visualization, reduce adenoma missing rates and enable in-vivo optical diagnosis. Methods can roughly be divided into three categories, ones that present improved visualization techniques (endoscopes with increased field of view, auxiliary imaging devices, so called addon devices), ones that enable more detail tissue characterization presenting the possibility for virtual biopsy (conventional or virtual chromoendoscopy, confocal laser endomicroscopy and endocytoscopy), and other minimally or non-invasive techniques.Further investigation is needed, but hopefully these innovations with continuous technical improvement might help to reduce the colorectal cancer incidence and mortality.

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Novel Endocuff-assisted Colonoscopy Significantly Increases the Polyp Detection Rate

Abstract: The use of the EC is feasible and safe with significantly higher polyp detection rates, especially for those located in the sigmoid region. The cuff system has the potential to improve the accuracy of screening colonoscopies.

Cited by 105 publications

References 23 publications

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

Endoscopic Improvement of the Adenoma Detection Rate during Colonoscopy - Where Do We Stand in 2015?

New Developments in Mechanical Enhancement of Colonoscopy: Cuffs, Caps and Rings

Advances in endoscopic diagnosis of colorectal cancer

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