Novel Extraction Techniques: An Effective Way to Retrieve the Bioactive Compounds from Saffron (<i>Crocus Sativus</i>)

Rahaman, Abdul; Kumari, Ankita; Farooq, Muhammad Adil; Zeng, Xin‐An; Hassan, Sadia; Khalifa, Ibrahim; Aadil, Rana Muhammad; Chughtai, Muhammad Farhan Jahangir; Khaliq, Adnan; Ahmad, Nabeel; Wajid, Mohd Anas

doi:10.1080/87559129.2021.1967377

Cited by 10 publications

(8 citation statements)

References 143 publications

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“…Extracting bioactive components from saffron necessitates ongoing research into environmentally and economically viable extraction strategies ( 38 , 39 ). Traditional extraction procedures are time-consuming and necessitate a large amount of solvent ( 40 ).…”

Section: Extraction Of Crocin By Conventional Methods and Novel Techn...mentioning

confidence: 99%

“…Traditional extraction procedures are time-consuming and necessitate a large amount of solvent ( 40 ). As a result, novel extraction strategies for extracting bioactive components from saffron have been devised, reducing extraction time and solvent usage while improving extract extraction yield and quality ( 38 ). Several approaches have been developed to extract bioactive components from saffron with maximum extraction and purity efficiency ( 38 ).…”

Section: Extraction Of Crocin By Conventional Methods and Novel Techn...mentioning

confidence: 99%

“…As a result, novel extraction strategies for extracting bioactive components from saffron have been devised, reducing extraction time and solvent usage while improving extract extraction yield and quality ( 38 ). Several approaches have been developed to extract bioactive components from saffron with maximum extraction and purity efficiency ( 38 ). It is confirmed that, compared to traditional procedures, the targeted bioactive components can be extracted more efficiently in terms of solvent volume and extraction time by employing the right extraction method ( 41 – 43 ).…”

Section: Extraction Of Crocin By Conventional Methods and Novel Techn...mentioning

confidence: 99%

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Crocin: Functional characteristics, extraction, food applications and efficacy against brain related disorders

Ali

Kousar

et al. 2022

Front. Nutr.

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Crocin is a bioactive compound that naturally occurs in some medicinal plants, especially saffron and gardenia fruit. Different conventional and novel methods are used for its extraction. Due to some control conditions, recent methods such as ultrasonic extraction, supercritical fluid extraction, enzyme-associated extraction, microwave extraction, and pulsed electric field extraction are widely used because these methods give more yield and efficiency. Crocin is incorporated into different food products to make functional foods. However, it can also aid in the stability of food products. Due to its ability to protect against brain diseases, the demand for crocin has been rising in the pharmaceutical industry. It also contain antioxidant, anti-inflammatory, anticancer and antidepressant qualities. This review aims to describe crocin and its role in developing functional food, extraction, and bioavailability in various brain-related diseases. The results of the literature strongly support the importance of crocin against various diseases and its use in making different functional foods.

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Section: Extraction Of Crocin By Conventional Methods and Novel Techn...mentioning

confidence: 99%

Section: Extraction Of Crocin By Conventional Methods and Novel Techn...mentioning

confidence: 99%

Section: Extraction Of Crocin By Conventional Methods and Novel Techn...mentioning

confidence: 99%

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Crocin: Functional characteristics, extraction, food applications and efficacy against brain related disorders

Ali

Kousar

et al. 2022

Front. Nutr.

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“…Saffron has been grown for flower and metabolites from the dried stigma. Picrocrocin, kaempferol, safranal, phenol, delphinidin, flavonoid, and crocetin are the primary phytochemicals in saffron; and they have good quality bioactivity and antioxidant potential [ 5 ]. After chemical analysis, fat, carbohydrates, minerals, vitamins, and other secondary metabolites such as anthocyanins, carotenoids, flavonoids, and terpenes have been discovered in saffron stigmas [ 11 ].…”

Section: Overview Of the Phytochemicals From Saffronmentioning

confidence: 99%

“…Traditional extraction procedures take a long time and require a large amount of solvent. Novel extraction strategies for extracting bioactive components from saffron have been developed, reducing extraction time and solvent usage while improving extract quality and yield [ 5 ]. There are wide and traditional medicinal uses of saffron in Tibetan medicine, Persian medicine, Ayurvedic medicine, and traditional Chinese medicine; and also, been used as an antibacterial, antidepressant, digestive, anticancer, and anticonvulsant [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Potential Role of Phytochemical Extract from Saffron in Development of Functional Foods and Protection of Brain-Related Disorders

Maqbool

Arshad

Ali

et al. 2022

Oxidative Medicine and Cellular Longevity

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The present review is designed to measure the effects of saffron extract in functional foods and its pharmacological properties against various disorders. Saffron is a traditional medicinal plant used as a food additive. The stigma of saffron has bioactive compounds such as safranal, crocin, crocetin, picrocrocin, kaempferol, and flavonoid. These bioactive compounds can be extracted using conventional (maceration, solvent extraction, soxhlet extraction, and vapor or hydrodistillation) and novel techniques (emulsion liquid membrane extraction, ultrasound-assisted extraction, enzyme-associated extraction, pulsed electric field extraction, microwave-assisted extraction, and supercritical fluid extraction). Saffron is used as a functional ingredient, natural colorant, shelf-life enhancer, and fortifying agent in developing different food products. The demand for saffron has been increasing in the pharma industry due to its protection against cardiovascular and Alzheimer disease and its antioxidant, anti-inflammatory, antitumor, and antidepressant properties. Conclusively, the phytochemical compounds of saffron improve the nutrition value of products and protect humans against various disorders.

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Encapsulation of Lacticaseibacillus rhamnosus by Extrusion Method to Access the Viability in Saffron Milk Dessert and Under Simulated Gastrointestinal Conditions

Ganje,

Sekhavatizadeh,

Teymouri

et al. 2024

Food Science & Nutrition

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The effectiveness of probiotics in delivering health benefits may be associated with their capacity to maintain a minimum concentration of 106 CFU/g during food storage and to successfully colonize the gastrointestinal tract (GI). Lacticaseibacillus rhamnosus (LR) is a probiotic that does not exhibit adequate stability under harsh conditions. To enhance the survival capacity of LR during gastrointestinal storage, alginate (ALG) was used as a primary encapsulating layer through extrusion microencapsulation. Subsequently, camelina seed mucilage (CSM) and camelina seed protein (CSP) were applied as secondary layers at varying concentrations (0%–4%). Among the tested formulations, ALG‐CSM‐CSP (1.5%, 4%, 4% w/w) exhibited significantly higher encapsulation efficiency (94.15%) and provided appropriate LR encapsulation in SEM image. Three saffron milk desserts (SMD) containing free LR (FLR), microencapsulated LR (MLR), and a control (C) were prepared, followed by physicochemical and microbiological assessments of the samples. The result showed that at the end of storage, SMD had the lowest pH (6.21), the highest acidity (30°D), and maintained the permissible limit of probiotic bacteria (6.7 log cfu/mL) among the samples. In GI, the MLR and FLR survival rates were 43% and 45.4%, respectively on the 14th day of storage, respectively. The MLR hardness (313.70 g), adhesiveness (2.01 mJ), chewiness (9.36) and gumminess (58.8) had the greatest values among the samples. Moreover, SEM images showed a relatively denser structure for MLR. In conclusion, this study highlights the potential of CSM and CSP to protect probiotics, offering valuable insights for developing new functional foods with improved survival during storage and GI.

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Novel Extraction Techniques: An Effective Way to Retrieve the Bioactive Compounds from Saffron (Crocus Sativus)

Cited by 10 publications

References 143 publications

Crocin: Functional characteristics, extraction, food applications and efficacy against brain related disorders

Crocin: Functional characteristics, extraction, food applications and efficacy against brain related disorders

Potential Role of Phytochemical Extract from Saffron in Development of Functional Foods and Protection of Brain-Related Disorders

Encapsulation of Lacticaseibacillus rhamnosus by Extrusion Method to Access the Viability in Saffron Milk Dessert and Under Simulated Gastrointestinal Conditions

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