Novel gallium-based voltammetric sensor for sensitive detection of cysteine

Selçuk, Kadir; Çağlar, Aykut; Aktaş, Nahit; Kıvrak, Hilal

doi:10.1016/j.jpcs.2022.110836

Cited by 4 publications

(1 citation statement)

References 38 publications

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“…Even though various techniques are adopted for the sensing of Cys like spectroscopy and voltammetry, [19][20][21][22][23][24][25] the requirement of speci c chromophores for speci c analytes, various analytes pretreatment steps, highly expensive instruments, high energy consumption and large number of synthetic solvents limits the applicability. On the other hand, some methods of Cys detection suffer disadvantages due to long reaction time, limits in detection, involvement of highly sophisticated machinery, and technicians as well as suitable physical conditions and high investment.…”

Section: Introductionmentioning

confidence: 99%

Bioinspired 5-caffeoylquinic acid capped silver nanoparticles using Coffee arabica leaf extract for high-sensitive cysteine detection

Haridas¹,

Bhattacharya

Varma³

et al. 2023

Preprint

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Along with health concern, choosing of plants as bioactive phytochemical source to synthesize nanoparticles is highly demanding due to the biocompatibility, nontoxicity, and cost-effectiveness over other available physical and chemical methods. Here, for the first time, Coffee arabica leaf extracts (CAE) were used to produce highly stable silver nanoparticles (AgNPs) and corresponding bio reduction, capping and stabilization mechanism mediated by 5-caffeoylquinic acid (5-CQA) is discussed. UV-Vis, FTIR, Raman spectroscopy, TEM, DLS and Zeta potential analyzer measurements were used to characterize these green synthesized NPs. The affinity of 5-CQA capped CAE-AgNPs to thiol moiety of amino acid is utilized for the selective as well as sensitive detection of L-cysteine (Cys) to a low detection limit of 0.1nM. Hence, the proposed novel, simple, eco-friendly, and economically sustainable method can provide a promising nanoplatform in the field of biosensors which is compliant with large-scale industrial production of AgNPs without aid of instruments.

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