Novel Hollow Polymer Shells by Colloid-Templated Assembly of Polyelectrolytes

Donath, Edwin; Sukhorukov, Gleb B.; Caruso, Frank; Davis, Sean A.; Möhwald, Helmuth

doi:10.1002/(sici)1521-3773(19980904)37:16<2201::aid-anie2201>3.3.co;2-5

Cited by 771 publications

(1,211 citation statements)

References 1 publication

Supporting

Mentioning

1,179

Contrasting

Unclassified

Order By: Relevance

“…The layer thickness can be controlled in the nanometer range by the number of adsorbed layers. Polyelectrolyte microcapsules (PMCs) can be prepared by this layerby-layer deposition process on colloidal templates with subsequent dissolution of the particle core [886]. Hollow, spherical capsules with diameters of 20 nm-20 mm and shell thicknesses of 10-50 nm have been prepared by this technique.…”

Section: Mechanical Properties Of Microcapsulesmentioning

confidence: 99%

Force measurements with the atomic force microscope: Technique, interpretation and applications

Butt

Cappella

Kappl

2005

Surface Science Reports

3,242

2,949

View full text Add to dashboard Cite

Section: Mechanical Properties Of Microcapsulesmentioning

confidence: 99%

Force measurements with the atomic force microscope: Technique, interpretation and applications

Butt

Cappella

Kappl

2005

Surface Science Reports

3,242

2,949

View full text Add to dashboard Cite

“…4 This LbL deposition protocol has been widely used for the development of functional microcapsules. 39 Microcapsules are usually prepared by the electrostatic deposition of polyelectrolytes, although LbL films deposited through hydrogen bonding and biological affinity can also be used for microcapsule construction.…”

Section: ·4 Lbl Microcapsulesmentioning

confidence: 99%

“…Möhwald and coworkers reported the preparation of hollow microcapsules by the LbL deposition of synthetic polyelectrolytes on the surface of microparticles, followed by dissolution of the core particles. 4 They then proposed the possible use of LbL microcapsules for the encapsulation and controlled release of drugs. LbL deposition is a bottom-up nanofabrication technique that relies on the molecular interactions of materials, which is distinct from previous methods for the preparation of polymer films and microcapsules.…”

Section: Introductionmentioning

confidence: 99%

Layer-by-layer Thin Films and Microcapsules for Biosensors and Controlled Release

2012

View full text Add to dashboard Cite

We present an overview of the preparation and properties of layer-by-layer (LbL) deposited thin films and microcapsules in relation to their use in the development of biosensors and controlled release systems. Enzyme biosensors can be constructed by immobilizing enzymes on the surface of electrodes by LbL deposition without loss of their catalytic activity. In addition to synthetic polymers, binding proteins, such as avidin and lectin, are also used for constructing LbL films through avidin-biotin and lectin-sugar interactions. The performance characteristics of LbL film-based biosensors can be tuned by controlling the number of layers and by the choice of film components. The permeability of polyelectrolyte LbL films to ions and molecules is discussed in relation to the use of the films for eliminating interference in biosensors. The possible use of polysaccharide LbL film-coated electrodes for the construction of biosensors is highlighted, and examples of LbL film-and microcapsule-based optical sensors are described. We then focus on the use of LbL films and microcapsules as vehicles for controlled release, in particular on recent progress in the controlled release of insulin from LbL films and microcapsules. LbL films composed of insulin and polymers are sensitive to environmental pH, and release insulin in response to pH changes, suggesting that insulin LbL films can be used in the development of orally administered insulin. The construction of glucose-dependent insulin release systems using LbL insulin microcapsules functionalized with phenylboronic acid, lectin, and glucose oxidase is also examined.

show abstract

“…This method is now widely used for the lamination of oppositely charged polymers, polymers with proteins, and organic with inorganic compounds in the molecular thickness. Preparation of the layer-bylayer assembled ultrathin hollow polymer shells (or nanotubes) has been extensively investigated by Caruso et al [15][16][17][18][19] and by other groups. [20][21][22][23][24][25][26] The preparation of free-standing ultrathin films by this approach has been studied by several groups.…”

Section: Nanomembrane Formation By Layer-by-layer Assemblymentioning

confidence: 99%

Development of Fabrication of Giant Nanomembranes

Watanabe

Vendamme

Kunitake

2007

Bulletin of the Chemical Society of Japan

View full text Add to dashboard Cite

Large nanomembranes, which are characterized by aspect ratios (size/thickness) of greater than one million, are described. The combination of nanometer thickness and macroscopic size facilitates important applications in materials separation, selective transport and electrochemical devices. In the past, only small pieces of nanomembranes have been fabricated, in spite of intensive research. We describe here the first examples of a general fabrication procedure. Spin coating of the precursor solutions on appropriate underlayer was effectively used to prepare 10-30 nm thick nanomembranes of metal oxides, interpenetrating network of cross-linked acrylate with metal oxide, and highly cross-linked organic polymers (epoxy resin, etc.). The underlayer is composed of an affinity (e.g., poly(vinyl alcohol)) layer and/ or sacrificial layer, and the role of these layers is discussed. Some of the mechanical properties of nanomembranes were measured by using a bulge test and a compression method. The nanomembranes of the organic and inorganic hybrids and the purely organic resins were surprisingly robust and defect-free.

show abstract

Novel Hollow Polymer Shells by Colloid-Templated Assembly of Polyelectrolytes

Cited by 771 publications

References 1 publication

Force measurements with the atomic force microscope: Technique, interpretation and applications

Force measurements with the atomic force microscope: Technique, interpretation and applications

Layer-by-layer Thin Films and Microcapsules for Biosensors and Controlled Release

Development of Fabrication of Giant Nanomembranes

Contact Info

Product

Resources

About