Novel interactions between iron and n‐3 fatty acids in cognition and immune function

Abstract

Many children, particularly from low‐ and middle‐income countries, may suffer from both iron deficiency and inadequate omega‐3 fatty acid intake due to poor quality diets. Both, iron and omega‐3 fatty acids are important for the development and functioning of the brain and immune system. Using a translational research approach, we therefore investigated potential interactive effects of iron and omega‐3 fatty acid deficiencies and supplementation on cognition and immune‐related outcomes. Our results indicate that in children with iron deficiency and poor omega‐3 fatty acid intake, it may be crucial to administer iron in combination with omega‐3 long‐chain polyunsaturated fatty acids to ensure optimal cognition and immune function.