2021
DOI: 10.52711/0974-360x.2021.00365
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Novel Method Development for Metformin, Ivabradine, Metoprolol and Ertugliflozin and its Validation in API and Pharmaceutical Dosage Form by RPHPLC Method

Abstract: Present investigation is based upon a new method development and validation for the simultaneous estimation of drugs comes under the classification of anti-hypertensive and anti-diabetic. For the proposed method metformin, ivabradine, metoprolol and ertugliflozin drugs were selected. The chromatographic separation was achieved by using mobile phase 0.01N potassium dihydrogen ortho phosphate buffer and acetonitrile (50:50) ratio and stationary phase of kromasil C18(250×4.6mm, 5µm) column. The retention times fo… Show more

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