Novel microinjector for carrying bone substitutes for bone regeneration in periodontal diseases

Tsai, Hsiao-Cheng; Li, Yi‐Chen; Young, Tai‐Horng; Chen, Min-Huey

doi:10.1016/j.jfma.2014.10.009

Cited by 12 publications

(8 citation statements)

References 26 publications

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“…β-TCP has been used primarily in synthesizing biphasic or monophasic bioceramics and α-TCP is part of many bone cements. β-TCP has been used more extensively in clinical applications of dentistry, maxillofacial surgery, tissue engineering and orthopedics than α-TCP [163][164][165] . In dental composite, TCP as a filler has been reported to increase water absorption due to the loss of minerals when it comes into contact with water, which further causes weakening of the mechanical strength of filling.…”

Section: Tcp/mcpm Based Dental Resinsmentioning

confidence: 99%

A review of bioceramics-based dental restorative materials

Khan

Syed

2019

Dent. Mater. J.

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Currently, much has been published related to conventional resin-based composites and adhesives; however, little information is available about bioceramics-based restorative materials. The aim was to structure this topic into its component parts and to highlight the translational research that has been conducted up to the present time. A literature search was done from indexed journals up to September 2017. The main search terms used were based on dental resin-based composites, dental adhesives along with bioactive glass and the calcium phosphate family. The results showed that in 123 articles, amorphous calcium phosphate (39.83%), hydroxyapatite (23.5%), bioactive glass (16.2%), dicalcium phosphate (5.69%), monocalcium phosphate monohydrate (3.25%), and tricalcium phosphate (2.43%) have been used in restorative materials. Moreover, seven studies were found related to a newly developed commercial bioactive composite. The utilization of bioactive materials for tooth restorations can promote remineralization and a durable seal of the tooth-material interface.

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Section: Tcp/mcpm Based Dental Resinsmentioning

confidence: 99%

A review of bioceramics-based dental restorative materials

Khan

Syed

2019

Dent. Mater. J.

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“…Finally, synthetic alloplastic biomaterials such as hydroxyapatite (HA) [ 149 , 150 , 151 ], TCP [ 152 ], a calcium-layered-polymer of polymethyl methacrylate and hydroxyethyl methacrylate [ 153 ], and bioactive glass [ 154 ] have been produced. For bone regeneration applications, injectable and absorbable scaffolds have been produced [ 155 , 156 ]. Calcium phosphate cements (CPCs) were made from powders combined with a liquid to make a paste [ 157 , 158 ].…”

Section: Regenerative Mechanisms Of Periodontal Tissuesmentioning

confidence: 99%

Human Umbilical Cord Mesenchymal Stem Cells: Current Literature and Role in Periodontal Regeneration

Shaikh

Shahzad

Tash

et al. 2022

Cells

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Periodontal disease can cause irreversible damage to tooth-supporting tissues such as the root cementum, periodontal ligament, and alveolar bone, eventually leading to tooth loss. While standard periodontal treatments are usually helpful in reducing disease progression, they cannot repair or replace lost periodontal tissue. Periodontal regeneration has been demonstrated to be beneficial in treating intraosseous and furcation defects to varied degrees. Cell-based treatment for periodontal regeneration will become more efficient and predictable as tissue engineering and progenitor cell biology advance, surpassing the limitations of present therapeutic techniques. Stem cells are undifferentiated cells with the ability to self-renew and differentiate into several cell types when stimulated. Mesenchymal stem cells (MSCs) have been tested for periodontal regeneration in vitro and in humans, with promising results. Human umbilical cord mesenchymal stem cells (UC-MSCs) possess a great regenerative and therapeutic potential. Their added benefits comprise ease of collection, endless source of stem cells, less immunorejection, and affordability. Further, their collection does not include the concerns associated with human embryonic stem cells. The purpose of this review is to address the most recent findings about periodontal regenerative mechanisms, different stem cells accessible for periodontal regeneration, and UC-MSCs and their involvement in periodontal regeneration.

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“…It was being used as an absorbable material in the development of tissue engineering scaffolds [ 96 ]. β-TCP had found more uses in clinical applications comparatively, and was also used in developing monophasic/biphasic bioceramics [ 97 , 98 , 99 , 100 , 101 ]. However, composites containing α-TCP were common in repairing bone defects [ 60 , 102 ].…”

Section: Bioactive Inorganic Materialsmentioning

confidence: 99%

Bioactive Inorganic Materials for Dental Applications: A Narrative Review

et al. 2022

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Over time, much attention has been given to the use of bioceramics for biomedical applications; however, the recent trend has been gaining traction to apply these materials for dental restorations. The bioceramics (mainly bioactive) are exceptionally biocompatible and possess excellent bioactive and biological properties due to their similar chemical composition to human hard tissues. However, concern has been noticed related to their mechanical properties. All dental materials based on bioactive materials must be biocompatible, long-lasting, mechanically strong enough to bear the masticatory and functional load, wear-resistant, easily manipulated, and implanted. This review article presents the basic structure, properties, and dental applications of different bioactive materials i.e., amorphous calcium phosphate, hydroxyapatite, tri-calcium phosphate, mono-calcium phosphate, calcium silicate, and bioactive glass. The advantageous properties and limitations of these materials are also discussed. In the end, future directions and proposals are given to improve the physical and mechanical properties of bioactive materials-based dental materials.

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Novel microinjector for carrying bone substitutes for bone regeneration in periodontal diseases

Abstract: The results confirmed the feasibility of this novel microinjector for dental applications to carry bone graft substitutes for the restoration of bone defects of periodontal disease.

Cited by 12 publications

References 26 publications

A review of bioceramics-based dental restorative materials

A review of bioceramics-based dental restorative materials

Human Umbilical Cord Mesenchymal Stem Cells: Current Literature and Role in Periodontal Regeneration

Bioactive Inorganic Materials for Dental Applications: A Narrative Review

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