Novel Molecularly Imprinted Polymer for the Determination of Carbendazim From Water and Food by Solid-Phase Extraction and High-Performance Liquid Chromatography

Akkbik, Mohammed; Hazer, Orhan

doi:10.1080/00032719.2017.1284859

Cited by 26 publications

(9 citation statements)

References 35 publications

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“…Various techniques have been reported for monitoring of thiophanate-methyl residues in various matrices. However, the Quick Easy Cheap Effective Rugged Safe (QuEChERS) method, in combination with LC-MS/MS has gained considerable attention for the sensitivity level they attain, beside the good selectivity and short analysis time (Akkbik and Hazer 2018;Chen et al 2013;Dong et al 2018;Economou et al 2009;Ferreira et al 2016;Qin 2016;Wu et al 2015;Yu et al 2017;Zhang et al 2012). On the other hand, solid phase extraction (SPE) methods have been frequently applied in combination with HPLC-DAD (Chen et al 2015;Soliman et al 2017;Veneziano et al 2004;Wu et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Dissipation behavior of thiophanate-methyl in strawberry under open field condition in Egypt and consumer risk assessment

Malhat

Abdallah

Ahmed

et al. 2020

Environ Sci Pollut Res

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Thiophanate methyl is a broad-spectrum benzimidazole fungicide extensively applied in pre-and post-harvest, for the control of a wide range of fruit and vegetable pathogens. In the current work, the residue behavior of thiophanate methyl after application on strawberries and an estimation of the consumer dietary exposure was performed. Supervised field trials were conducted in Egypt (Qaluobiya Governorate) as to investigate the residue dynamics and terminal residues at different PHIs of thiophanate methyl and its metabolite carbendazim in strawberries under Egyptian conditions. For the measurement of residues in fruits, a QuEChERSbased protocol coupled with LC-MS/MS was optimized and successfully validated at 0.01 mg kg −1. The half-life (t 1/2) of thiophanate methyl in strawberries was estimated, and a dietary risk assessment was performed employing both FAO/WHO and EFSA approaches.

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Section: Introductionmentioning

confidence: 99%

Dissipation behavior of thiophanate-methyl in strawberry under open field condition in Egypt and consumer risk assessment

Malhat

Abdallah

Ahmed

et al. 2020

Environ Sci Pollut Res

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“…To the best of our knowledge, little attention has been paid to fungicide dissipation in apple leaves, a non‐edible part which has no direct relation to human health. Various methods have been developed for the determination of TM and MBC in biological samples, including spectrophotographic assays (İlktaç, Aksuner, & Henden, ; Jiao et al, ), capillary electrophoresis (Picó, Rodrı́Guez, & Mañes, ), Raman imaging (Li, Sun, Pu, & Jayas, ), mass spectrometry (Yang et al, ), thin‐layer chromatography coupled with image analysis (Skowron, Zakrzewski, & Ciesielski, ), high‐performance liquid chromatography (Akkbik & Hazer, ; Sandahl, Mathiasson, & Jönsson, ; Singh, Foster, & Khan, ; Veneziano et al, ; Yu, Sun, Wang, He, & Feng, ; Zhang et al, ) and liquid chromatography–mass spectrometry (Chen et al, ; Chen et al, ; Chen, Cao, & Liu, ; Dong, Yang, Pang, & Hu, ; Dreassi et al, ; Economou, Botitsi, Antoniou, & Tsipi, ; Fernández‐Alba, Tejedor, Agüera, Contreras, & Garrido, ; Ferreira et al, ; Ferreira et al, ; Golge & Kabak, ; Morales, Ruiz, Oliva, & Barba, ; Qin et al, ; Wang & Leung, ; Wu, Chen, Li, & Fan, ; Zhang, Mei, Wang, Zhang, & Zhu, ). Among these methods, the Quick Easy Cheap Effective Rugged Safe (QuEChERS) method followed by UPLC–MS/MS detection has attracted more attention because of its satisfactory sensitivity, good selectivity and short analysis time (Bruzzoniti et al, ; Lehotay, ; Wilkowska & Biziuk, ).…”

Section: Introductionmentioning

confidence: 99%

Analysis of the dissipation kinetics of thiophanate‐methyl and its metabolite carbendazim in apple leaves using a modified QuEChERS–UPLC–MS/MS method

Wang

Lian

Dong

et al. 2018

Biomedical Chromatography

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As one of the main fungicides for the apple leaf disease control, thiophanate-methyl (TM) mainly exerts its fungicidal activity in the form of its metabolite carbendazim (MBC), whose dissipation kinetics is very distinct from that of its parent but has been paid little attention. The aim of this work was to investigate the dissipation kinetics of TM and its active metabolite MBC in apple leaves using a modified QuEChERS-UPLC-MS/MS method. The results showed that TM and MBC could be quickly extracted by this modified QuEChERS procedure with recoveries of 81.7-96.5%. The method linearity was in the range of 0.01-50.0 mg kg −1 with the quantification limit of 0.01 mg kg −1 . Then this method was applied to the analysis of fungicide dissipation kinetics in apple leaves. The results showed that the dissipation kinetics of TM for the test in 3 months can be described by a first-order kinetics model with a DT 50 (dissipation half-life) range of 5.23-6.03 days and the kinetics for MBC can be described by a firstorder absorption-dissipation model with the T max (time needed to reach peak concentration) range of 4.78-7.09 days. These models can scientifically describe the behavior of TM and MBC in apple leaves, which provides necessary data for scientific application.

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“…The adsorption process could be explained by the Langmuir model, which was based on the monolayer adsorption. q m values for the mycotoxins were in the range of 4.9–10.2 mg/g, which indicates the acceptable adsorption capacities for MSPE applications [27,28]. From Supporting Information Table S4, Langmuir constants (K L ) were in range of 8.4–26.3 L/mg.…”

Section: Resultsmentioning

confidence: 99%

Polyethyleneimine‐modified magnetic carbon nanotubes as solid‐phase extraction adsorbent for the analysis of multi‐class mycotoxins in milk via liquid chromatography–tandem mass spectrometry

Qiu

Qian

2020

J of Separation Science

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Polyethyleneimine‐modified magnetic multi‐walled carbon nanotubes were developed to extract 10 mycotoxins. Simple modification of polyethyleneimine was achieved on the magnetic substrate by using an epoxy‐containing silane agent as a linker. The resultant magnetic adsorbent was integrated with reverse phase and anion exchange interaction sites. Under optimal extraction conditions, only 20.0 mg adsorbent was used to extract the mycotoxins from 50.0 mL loading solution. The maximum adsorption capacities of the adsorbent toward the mycotoxins ranged from 4.9 to 10.2 mg/g. Adsorption and desorption were completed within 3.0 and 2.0 min, respectively. The adsorbent could be used for six repeated runs without evident change in extraction performance. The adsorbent combined with liquid chromatography–tandem mass spectrometry was applied further to analyze the mycotoxins in milk. The absolute recoveries of the 10 mycotoxins ranged from 88.3 to 103.5% with relative standard deviations that ranged from 2.4 to 6.5%, and their limits of detection were 0.003 to 0.442 μg/kg. The proposed adsorbent has great potential in the routine analysis of mycotoxins in ordinary analytical chemistry laboratory.

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Novel Molecularly Imprinted Polymer for the Determination of Carbendazim From Water and Food by Solid-Phase Extraction and High-Performance Liquid Chromatography

Cited by 26 publications

References 35 publications

Dissipation behavior of thiophanate-methyl in strawberry under open field condition in Egypt and consumer risk assessment

Dissipation behavior of thiophanate-methyl in strawberry under open field condition in Egypt and consumer risk assessment

Analysis of the dissipation kinetics of thiophanate‐methyl and its metabolite carbendazim in apple leaves using a modified QuEChERS–UPLC–MS/MS method

Polyethyleneimine‐modified magnetic carbon nanotubes as solid‐phase extraction adsorbent for the analysis of multi‐class mycotoxins in milk via liquid chromatography–tandem mass spectrometry

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