Desiccant agents (DAs) have drawn much interest from researchers and businesses because they offer a potential method for lowering environmental impact, increasing energy efficiency, and controlling humidity. As a result, they provide a greener option to conventional air conditioning systems. This review thoroughly analyzes current issues, obstacles, and future advancements in liquid desiccant agents (LDAs) for drying, air conditioning, and dehumidification applications. The importance of LDAs in lowering energy use and greenhouse gas emissions is highlighted, emphasizing their potential for environmentally friendly humidity control. The current review examines key parameters such as novel materials, enhancing desiccant qualities, integration with technologies, and long-term durability while examining recent developments in LDAs and investigating their applications in diverse industries. The main conclusions from the evaluated publications in this review are also highlighted, including developments in LDAs, new applications, and developing research fields. Overall, this review advances knowledge of LDAs and their potential to shift humidity control systems toward sustainability and energy efficiency.