Novel surface plasmon resonance (SPR)-based biosensor for pathogenic bacteria detection (PathoBactD)

Abstract

This paper presents a novel approach for pathogenic bacteria detection (PathoBactD) through the utilization of a surface plasmon resonance (SPR)-based biosensor. The sensor consists of a BK7 prism coated with silver (Ag), barium titanate (BaTiO3), and molybdenum diselenide (MoSe2) in the Kretschmann arrangement. The proposed SPR-based biological sensor incorporates the concept of attenuated total reflection (ATR) for accurate measurements. Various performance characteristics of the sensor, including sensitivity, figure of merit (FoM), signal-to-noise ratio (SNR), detection accuracy, and quality factor, have been thoroughly analyzed. The integration of BaTiO3 significantly enhances the sensor's capability for PathoBactD. To evaluate the impact of the BaTiO3 layer on the performance parameters of the MoSe2-based SPR biological sensor, a theoretical model employing the angular interrogation technique has been developed.